DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-lambda and opcml

DIOPT Version :9

Sequence 1:	NP_001334747.1	Gene:	DIP-lambda / 26067049	FlyBaseID:	FBgn0267428	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	301	Identity:	84/301 - (27%)
Similarity:	132/301 - (43%)	Gaps:	44/301 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 NTTVPIGRDISFTCVVDNLGHYRVAWIKSDSKAILGIHTHMVSLNPRLSVTHNGHNTWKLHISRV 122
            |.||..|......|.:||... ||||:  :...||.......||:||:.:.:...|.:.:.|..|
Zfish    41 NITVRQGDSAVLKCSMDNKVS-RVAWL--NRTTILFTGNEKWSLDPRVVLLNTAVNEYSIKILNV 102

  Fly   123 QINDSGSYMCQVNTDPM-KSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPK 186
            .:.|.|.|:|.:.|:.. :|...:|.|.||..|:|    ...|....||.::||||...|.|.|.
Zfish   103 NLYDEGPYVCSILTNKKPESTKVHLIVQVPARIVN----VSTDVSVNEGSNVSLMCLAIGRPEPS 163

  Fly   187 VLW--RREAGKEIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVY 249
            :||  |...|..|:             .|||.:.:|.:.:...|.|:||.||.|.|...:...|.
Zfish   164 ILWKFRSSKGNRIV-------------TEGEYVEMTGITKDMSGSYDCITSNDISPPDVRTVQVT 215

  Fly   250 VNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYRSE-------GNIKLHNGNKYNISEE 307
            ||:.|.:.. ::..|..|.::..|.|.....|.....|::.|       ..:|:.|..|.::
Zfish   216 VNYPPVISR-ARSTGTAVGQKGVLWCEASAVPLADFQWFKGERRILNGFNGVKIENKGKQSM--- 276

  Fly   308 VINIYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRL 348
                      ||..::::.|:|.|:|.::|.||.:.:.|.|
Zfish   277 ----------LTFFNVSEEDYGNYTCVAINTLGITNASIIL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-lambda	NP_001334747.1	None
opcml	NP_001005580.1	Ig	41..129	CDD:299845	27/90 (30%)
		IG_like	41..129	CDD:214653	27/90 (30%)
		IG_like	139..216	CDD:214653	28/89 (31%)
		IGc2	146..202	CDD:197706	22/68 (32%)
		I-set	219..307	CDD:254352	21/101 (21%)
		ig	223..307	CDD:278476	20/97 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4644
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.970