DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-lambda and Tmigd1

DIOPT Version :9

Sequence 1:	NP_001334747.1	Gene:	DIP-lambda / 26067049	FlyBaseID:	FBgn0267428	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001128501.1	Gene:	Tmigd1 / 363654	RGDID:	1307444	Length:	261	Species:	Rattus norvegicus

Alignment Length:	272	Identity:	66/272 - (24%)
Similarity:	116/272 - (42%)	Gaps:	58/272 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 TLACSIAFILIKAITITKCHAVAHIHGKGESEEIDPQFLAKLSNTTVPIGRDISFTCVVDNLGHY 79
            :|..|...:|:.::...:..:|..::|:.|...:|..:           |...|..|.|.|  |.
  Rat     8 SLTASQLLLLVLSLPQGRTSSVLTVNGRTEDYILDTYY-----------GIQASLECAVQN--HT 59

  Fly    80 R---VAWIKSDSKAILGIHTHMVSLNPRLSVTHNGH--NTWKLHISRVQINDSG-SYMCQVNTDP 138
            |   :.|.:...:..|                .||:  ||..:.:|.:..:|:| |:.|::..|.
  Rat    60 RDEELLWYREAGRVDL----------------KNGNKINTSSVCVSPINESDNGVSFTCKLQRDQ 108

  Fly   139 MKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRR-------EAGKE 196
            ..|::..|:|..||.:..:.....|     ||..:.|:|:|...|:.::||.|       |.|:.
  Rat   109 TVSITVVLNVTFPPLLSGNGFQTVE-----EGSDVRLVCNVKSNPQAQMLWYRNNSALVLEKGRH 168

  Fly   197 IILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVYVNFSPTVKAISQ 261
            .|.:|.          |..:|.:|.|::||.|.||||||:.: .:.:..|::.|.....|..|..
  Rat   169 QIQQTR----------ESFQLSITRVKKSDNGTYNCIASSSL-KTETMDFHLVVKDKVPVMPIEP 222

  Fly   262 LVGAPVEREVTL 273
            ::.|.|...:||
  Rat   223 IIAACVVVFLTL 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-lambda	NP_001334747.1	None
Tmigd1	NP_001128501.1	IG_like	130..211	CDD:214653	28/96 (29%)
		Ig strand B	138..142	CDD:409353	1/3 (33%)
		Ig strand C	151..155	CDD:409353	1/3 (33%)
		Ig strand E	177..181	CDD:409353	1/3 (33%)
		Ig strand F	191..196	CDD:409353	3/4 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11357
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910