DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-lambda and Prtg

DIOPT Version :9

Sequence 1:NP_001334747.1 Gene:DIP-lambda / 26067049 FlyBaseID:FBgn0267428 Length:548 Species:Drosophila melanogaster
Sequence 2:NP_001032740.2 Gene:Prtg / 315806 RGDID:1307157 Length:1193 Species:Rattus norvegicus


Alignment Length:435 Identity:93/435 - (21%)
Similarity:155/435 - (35%) Gaps:107/435 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 FLAKLSNTTVPIGRDISFTCVVDNLGHYRVAWIKSDSKAILGIHTHMVSLNPRLSVTHNGHNTWK 116
            |:.:..:.||.....:...|.....|..:|.|:|:.:|         :|.|.|:.|..||    .
  Rat    35 FMKEPQDATVTRKDPVFLDCQAHGEGPIKVTWLKNGAK---------LSENKRIQVLSNG----S 86

  Fly   117 LHIS-----RVQINDSGSYMC-QVNT-DPMKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSIS 174
            |:||     |.:.:|.|.|.| .||. ..:.|...:|.:    ..::..|.:|......|||...
  Rat    87 LYISEAEGRRGEQSDEGFYQCLAVNKYGAILSQKAHLTL----STISAFEVHPVSTEVPEGGVAR 147

  Fly   175 LMCSVTGVPRPKVLW--RREAGKEIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNG 237
            ..|.::..|...:.|  .|.|   :.:..|.|    ..::....|.:.:....|.|.|.|:|:..
  Rat   148 FSCKISSTPPAVITWEFNRTA---LPMTMDSR----VTALPSGVLQIYDAGPEDAGKYRCVAATH 205

  Fly   238 -------------IPPSVSKRFNVYVNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYR 289
                         :|.:.::.|     :.||:.|..|.|.|.:.:.|.|||:...:|||:..|.|
  Rat   206 AHKRKSMEASLTIVPANETRSF-----YMPTIIASPQNVTASLHQTVVLECMATGYPKPIISWSR 265

  Fly   290 SEGNIKLHNGNKYNISEEVINIYTWHL----NLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQE 350
                          :..:.|:::...:    ||.|..:.....|.|.|.:... |.....:.:..
  Rat   266 --------------LDHKSIDVFNTRVLGNGNLIISDVKLQHAGVYVCRATTP-GTRNFTVAMAT 315

  Fly   351 LRL---------PPKLTT--------------TPTPHMQTTGKSRRKHPASHKKGLNEVLRFQET 392
            |.:         |..||.              .|:|.|......||.|.....|..|..|     
  Rat   316 LTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRRIHSNGRIKMYNSKL----- 375

  Fly   393 HFANQIQQENEDHNEGFDLLKFTNSENS-NIVLESGHINSMINKE 436
             ..|||..|:       |.:....:||| ..||....:..:::::
  Rat   376 -VINQIIPED-------DAIYQCMAENSQGSVLSRARLTVVMSED 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-lambdaNP_001334747.1 None
PrtgNP_001032740.2 Ig 32..124 CDD:416386 26/101 (26%)
Ig strand A 32..35 CDD:409353 93/435 (21%)
Ig strand A' 38..44 CDD:409353 0/5 (0%)
Ig strand B 48..58 CDD:409353 1/9 (11%)
Ig strand C 62..68 CDD:409353 2/5 (40%)
Ig strand C' 70..73 CDD:409353 1/11 (9%)
Ig strand D 78..83 CDD:409353 2/4 (50%)
Ig strand E 85..91 CDD:409353 3/9 (33%)
Ig strand F 103..110 CDD:409353 3/6 (50%)
Ig strand G 114..124 CDD:409353 1/9 (11%)
Ig 131..218 CDD:416386 18/93 (19%)
Ig strand B 146..150 CDD:409353 0/3 (0%)
Ig strand C 159..163 CDD:409353 0/3 (0%)
Ig strand E 183..187 CDD:409353 1/3 (33%)
Ig strand F 197..202 CDD:409353 2/4 (50%)
Ig strand G 211..214 CDD:409353 0/2 (0%)
Ig_3 230..302 CDD:404760 22/85 (26%)
Ig strand B 247..251 CDD:409353 2/3 (67%)
Ig strand C 260..264 CDD:409353 0/3 (0%)
Ig strand E 282..286 CDD:409353 2/3 (67%)
Ig strand F 296..301 CDD:409353 2/4 (50%)
I-set 322..407 CDD:400151 22/97 (23%)
Ig strand C 352..357 CDD:409353 1/4 (25%)
Ig strand C' 359..362 CDD:409353 1/2 (50%)
Ig strand D 367..371 CDD:409353 1/3 (33%)
Ig strand E 373..378 CDD:409353 1/10 (10%)
Ig strand F 387..394 CDD:409353 0/6 (0%)
Ig strand G 398..407 CDD:409353 2/8 (25%)
FN3 414..507 CDD:238020
FN3 512..605 CDD:238020
fn3 619..694 CDD:394996
FN3 721..809 CDD:238020
FN3 816..906 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 974..1018
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1078..1193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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