DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-lambda and Igsf9b

DIOPT Version :9

Sequence 1:	NP_001334747.1	Gene:	DIP-lambda / 26067049	FlyBaseID:	FBgn0267428	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	372	Identity:	88/372 - (23%)
Similarity:	140/372 - (37%)	Gaps:	82/372 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LIKAITITKCHAVAHIHGKGESEEIDPQFLAKLSNTTVPIGRDISFTC-----VVDNLGHYRVAW 83
            ||.::..|:.......||..|    :|:|:      |...|..:...|     |......|.|.|
  Rat     8 LIASVISTRGLVAQVAHGLRE----EPEFV------TARAGEGVVLRCDVIHPVTGQPPPYVVEW 62

  Fly    84 IKSDSKAILGIHT--------HMVSLNPRLSVTHNGHNTWKLHISRVQINDSGSYMCQV-----N 135
            .|      .|:..        :...::|..:...:.|:...|.:.:|:..|.|.|.|:|     .
  Rat    63 FK------FGVPIPIFIKFGYYPPHVDPEYAGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQ 121

  Fly   136 TDPMKSLSG-YLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREAGKEIIL 199
            .|...:.|. :|.:..||.....|   |:....:|||||::.|:..|.|:|.|.|.:|.   .:|
  Rat   122 YDTFHNGSWVHLTINAPPTFTETP---PQYIEAKEGGSITMTCTAFGNPKPIVTWLKEG---TLL 180

  Fly   200 RTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASN--------------GIPPSVSKRFNVYV 250
            ...|:    ::..:|. |.:|:|.|.|.|.|.|.|.:              |.|..||...|:.|
  Rat   181 SASGK----YQVSDGS-LTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITV 240

  Fly   251 NFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLN-GWYRSEGNIKLHNGNKYNISEEVINIYTW 314
            |.|               ::..|.|..|.:|..|. .||..:.|:...|..|..:...:..
  Rat   241 NIS---------------QDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDG---- 286

  Fly   315 HLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTP 361
              .|.|..:...|.|.|:|...|:||:|.|......::.|.::...|
  Rat   287 --TLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMP 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-lambda	NP_001334747.1	None
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273	15/79 (19%)
		I-set	139..225	CDD:369462	27/96 (28%)
		Ig	229..321	CDD:386229	28/112 (25%)
		Ig	<353..414	CDD:386229
		Ig	438..502	CDD:319273
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010