DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-lambda and Vsig10

DIOPT Version :9

Sequence 1:	NP_001334747.1	Gene:	DIP-lambda / 26067049	FlyBaseID:	FBgn0267428	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001258265.1	Gene:	Vsig10 / 304529	RGDID:	1565800	Length:	564	Species:	Rattus norvegicus

Alignment Length:	336	Identity:	78/336 - (23%)
Similarity:	130/336 - (38%)	Gaps:	71/336 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 AHIHGKGESEEIDPQFLAKLSNTTV--PIGRDISFTCVVDNLGHYRVAWIKSDSKAILGIHTH-- 97
            |||       :::......|.|.|:  ..|..:.|:|.........|.|         .|.||
  Rat   150 AHI-------DVNISATGTLPNGTLYAARGSQVDFSCCSAAQPPPEVEW---------WIQTHSS 198

  Fly    98 -MVSLNPRLSVTHNGHNTWKLHISRVQINDSGSYMC---QVNTDPMKSLSGYLDVVVPPDILNHP 158
             ..||...||.     |::.|.:  :..|..|:|.|   .|.:...:.::..|.|..||.  :.|
  Rat   199 VSESLGKNLSA-----NSFTLML--MSKNLQGNYTCSATNVLSRRQRKVTTELLVYWPPP--SAP 254

  Fly   159 EHNPEDGVCQEGGSISLMCSVT-GVPRPKVLWRREAGKEIILRTDGRDKTGFKSVEGERLVLTNV 222
            :.:.  |:..|..::.|.|:.. |.|.|..||..|.|..::    |..|.         ..|:..
  Rat   255 QCSA--GLSPESANLELTCNWDGGYPDPTFLWTEEPGGVVV----GNSKL---------QTLSPS 304

  Fly   223 QRSDMGGYNCIASNGIPPSVSKRFNVYVNFSPTVKAISQ---LVGAPVEREVTLECIVEVFPKPL 284
            |.|:...:.|:.|:.:.|.......|.:: ||.:.:...   |||.    :|||.|.||....|.
  Rat   305 QLSEGKKFKCVGSHILGPESGASCVVQIS-SPLLASRPMKTCLVGG----DVTLTCQVEGANPPA 364

  Fly   285 N-GWYR--SEGNIKLHNGNKYNISEEVINIYTWHLNLTIRHLTK-SDFGTYSCSSVNALGKSESL 345
            . .|.|  ::....:...::|.|:::     ....:|||.:.:: .|.|.|.|.:.|.:|
  Rat   365 RIQWLRNLTQPETAIQPSSRYVITQQ-----GQSSSLTIHNCSQDQDGGFYFCRAENPVG----- 419

  Fly   346 IRLQELRLPPK 356
            :|..::.|..|
  Rat   420 VRAADIWLSVK 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-lambda	NP_001334747.1	None
Vsig10	NP_001258265.1	Ig	60..146	CDD:299845
		IG_like	60..145	CDD:214653
		IG_like	165..246	CDD:214653	21/96 (22%)
		Ig	175..241	CDD:143165	18/81 (22%)
		Ig_3	255..318	CDD:290638	17/77 (22%)
		IG_like	347..429	CDD:214653	24/95 (25%)
		Ig	351..426	CDD:143165	21/84 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010