DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-lambda and Lsamp

DIOPT Version :9

Sequence 1:NP_001334747.1 Gene:DIP-lambda / 26067049 FlyBaseID:FBgn0267428 Length:548 Species:Drosophila melanogaster
Sequence 2:XP_038944182.1 Gene:Lsamp / 29561 RGDID:71102 Length:378 Species:Rattus norvegicus


Alignment Length:331 Identity:102/331 - (30%)
Similarity:154/331 - (46%) Gaps:36/331 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 NTTVPIGRDISFTCVVDNLGHYRVAWIKSDSKAILGIHTHMVSLNPRLSVTHNGHNTWKLHISRV 122
            |.||..|......|||:: .:.:|||: :.|..|...|... ||:||:.:.......:.|.|.:|
  Rat    57 NITVRQGDTAILRCVVED-KNSKVAWL-NRSGIIFAGHDKW-SLDPRVELEKRHALEYSLRIQKV 118

  Fly   123 QINDSGSYMCQVNT--DPMKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRP 185
            .:.|.|||.|.|.|  :| |:...||.|.|||.|.|    ...|....||.:::|:|...|.|.|
  Rat   119 DVYDEGSYTCSVQTQHEP-KTSQVYLIVQVPPKISN----ISSDVTVNEGSNVTLVCMANGRPEP 178

  Fly   186 KVLWRREAGKEIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVYV 250
            .:.||.       |...||:..|    |.|.|.:..:.|...|.|.|.|:|.:..:..|:..|.|
  Rat   179 VITWRH-------LTPLGREFEG----EEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTV 232

  Fly   251 NFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYRSEGNIKLHNGNKYNISEEVINIYTWH 315
            |:.||:.. |:...|...|:.:|:|.....|.|...|||.:..|...||.:...:|       ..
  Rat   233 NYPPTITE-SKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTE-------GQ 289

  Fly   316 LNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTP--HMQTTGKSRRKHPAS 378
            .:||:.::|:..:|.|:|.:.|.||.:.:.:.|.:..||    |.|.|  .:.||...::|.|.|
  Rat   290 SSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFKRVLP----TVPHPIQEIGTTVHFKQKGPGS 350

  Fly   379 HKKGLN 384
             .:|:|
  Rat   351 -VRGIN 355

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-lambdaNP_001334747.1 None
LsampXP_038944182.1 Ig 55..145 CDD:416386 31/91 (34%)
FR1 55..71 CDD:409353 4/13 (31%)
Ig strand A' 56..62 CDD:409353 3/4 (75%)
Ig strand B 64..72 CDD:409353 1/7 (14%)
CDR1 72..76 CDD:409353 1/4 (25%)
FR2 77..84 CDD:409353 3/7 (43%)
Ig strand C 77..83 CDD:409353 3/6 (50%)
CDR2 85..95 CDD:409353 3/9 (33%)
Ig strand C' 87..90 CDD:409353 1/2 (50%)
Ig strand C' 92..95 CDD:409353 1/2 (50%)
FR3 96..131 CDD:409353 12/34 (35%)
Ig strand D 100..107 CDD:409353 1/6 (17%)
Ig strand E 110..116 CDD:409353 1/5 (20%)
Ig strand F 123..131 CDD:409353 4/7 (57%)
CDR3 132..136 CDD:409353 1/3 (33%)
Ig strand G 136..145 CDD:409353 4/9 (44%)
FR4 138..145 CDD:409353 2/6 (33%)
Ig_3 148..218 CDD:404760 26/84 (31%)
Ig strand A' 155..160 CDD:409353 1/4 (25%)
Ig strand B 166..173 CDD:409353 2/6 (33%)
Ig strand C 179..184 CDD:409353 1/4 (25%)
Ig strand D 190..193 CDD:409353 1/2 (50%)
Ig strand E 197..203 CDD:409353 2/5 (40%)
Ig strand F 210..217 CDD:409353 3/6 (50%)
Ig strand G 224..232 CDD:409353 2/7 (29%)
Ig_3 235..311 CDD:404760 22/83 (27%)
Ig strand B 252..256 CDD:409353 1/3 (33%)
Ig strand C 265..269 CDD:409353 0/3 (0%)
Ig strand E 290..294 CDD:409353 1/3 (33%)
Ig strand F 304..309 CDD:409353 2/4 (50%)
Ig strand G 318..321 CDD:409353 0/2 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 45 1.000 Domainoid score I11853
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4382
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8971
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
87.970

Return to query results.
Submit another query.