DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-lambda and Ntm

DIOPT Version :9

Sequence 1:NP_001334747.1 Gene:DIP-lambda / 26067049 FlyBaseID:FBgn0267428 Length:548 Species:Drosophila melanogaster
Sequence 2:NP_001344522.1 Gene:Ntm / 235106 MGIID:2446259 Length:367 Species:Mus musculus


Alignment Length:385 Identity:110/385 - (28%)
Similarity:166/385 - (43%) Gaps:59/385 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 KTARIKMYNGTLACSIAFILIKAITITKCHAVAHIHG----KGESEEIDPQFLAKLSNTTVPIGR 65
            ||.:.||:|     ||::.:...:.     |:....|    .|     |..|...:.|.||..|.
Mouse     2 KTIQAKMHN-----SISWAIFTGLA-----ALCLFQGVPVRSG-----DATFPKAMDNVTVRQGE 51

  Fly    66 DISFTCVVDNLGHYRVAWIKSDSKAILGIHTHMVSLNPRLSVTHNGHNTWKLHISRVQINDSGSY 130
            ..:..|.:|| ...||||:  :...||........|:||:.:..|....:.:.|..|.:.|.|.|
Mouse    52 SATLRCTIDN-RVTRVAWL--NRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPY 113

  Fly   131 MCQVNTD--PMKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREA 193
            .|.|.||  | |:...:|.|.|.|.|:    ....|....||.:|||.|..||.|.|.|.||..:
Mouse   114 TCSVQTDNHP-KTSRVHLIVQVSPKIV----EISSDISINEGNNISLTCIATGRPEPTVTWRHIS 173

  Fly   194 GKEIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVYVNFSPTVKA 258
            .|.:          ||.| |.|.|.:..:.|...|.|.|.|||.:...|.:|..|.||:.|.:..
Mouse   174 PKAV----------GFVS-EDEYLEIQGITREQSGEYECSASNDVAAPVVRRVKVTVNYPPYISE 227

  Fly   259 ISQLVGAPVEREVTLECIVEVFPKPLNGWYRS-----EGNIKLHNGNKYNISEEVINIYTWHLNL 318
             ::..|.||.::.||:|.....|.....|::.     ||...:...|:..:|:           |
Mouse   228 -AKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGVKVENRPFLSK-----------L 280

  Fly   319 TIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTPHMQTTGKSRRKHPAS 378
            |..::::.|:|.|:|.:.|.||.:.:.|.|.||..|  .::|....::||..:..|.|.:
Mouse   281 TFFNVSEHDYGNYTCVASNKLGHTNASIMLFELNEP--TSSTLLQEVKTTALTPWKGPGA 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-lambdaNP_001334747.1 None
NtmNP_001344522.1 Ig 44..132 CDD:416386 29/91 (32%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 1/7 (14%)
CDR1 59..63 CDD:409353 2/4 (50%)
FR2 64..70 CDD:409353 4/7 (57%)
Ig strand C 64..70 CDD:409353 4/7 (57%)
CDR2 71..83 CDD:409353 2/11 (18%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 10/33 (30%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 2/3 (67%)
Ig strand G 123..132 CDD:409353 3/9 (33%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 136..205 CDD:404760 28/83 (34%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 4/8 (50%)
Ig strand F 197..205 CDD:409353 4/7 (57%)
Ig_3 222..299 CDD:404760 19/88 (22%)
putative Ig strand A 223..229 CDD:409353 1/6 (17%)
Ig strand B 239..243 CDD:409353 2/3 (67%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 2/14 (14%)
Ig strand F 292..297 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 45 1.000 Domainoid score I12107
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4449
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8732
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
76.970

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