DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-lambda and Iglon5

DIOPT Version :9

Sequence 1:NP_001334747.1 Gene:DIP-lambda / 26067049 FlyBaseID:FBgn0267428 Length:548 Species:Drosophila melanogaster
Sequence 2:NP_001157990.1 Gene:Iglon5 / 210094 MGIID:2686277 Length:336 Species:Mus musculus


Alignment Length:317 Identity:91/317 - (28%)
Similarity:142/317 - (44%) Gaps:35/317 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 QFLAKLSNTTVPIGRDISFTCVVDNLGHY-RVAWIKSDSKAILGIHTHMVSLNPRLSVTHNGHNT 114
            :|.:...|.||..|.:.:.:|.:|.  |. ||||:...:  ||.......:.:||:.:..|....
Mouse    34 EFSSPADNYTVCEGDNATLSCFIDE--HVTRVAWLNRSN--ILYAGNDRWTSDPRVRLLINTPEE 94

  Fly   115 WKLHISRVQINDSGSYMCQVNT--DPMKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMC 177
            :.:.|::|.:.|.|.|.|...|  .|. :...||.|.||..|:|  ..:|.  ...|||:::|:|
Mouse    95 FSILITQVGLGDEGLYTCSFQTRHQPY-TTQVYLIVHVPARIVN--ISSPV--AVNEGGNVNLLC 154

  Fly   178 SVTGVPRPKVLWRREAGKEIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSV 242
            ...|.|.|.|.||:       ||      .||.| |||.|.::::||...|.|.|:..||:..:.
Mouse   155 LAVGRPEPTVTWRQ-------LR------DGFTS-EGEILEISDIQRGQAGEYECVTHNGVNSAP 205

  Fly   243 -SKRFNVYVNFSPTVKAISQLVGAPVEREVTLECIVEVFPKPLNGWYRSEGNIKLHNGNKYNISE 306
             |:|..|.||:.||:..::....| :.|...|.|.....|.....||:.:..:...:.....:..
Mouse   206 DSRRVLVTVNYPPTITDVTSARTA-LGRAALLRCEAMAVPPADFQWYKDDRLLSSGSAEGLKVQT 269

  Fly   307 EVINIYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTP 363
            |.........|::.||     :|.|:|.:.|.||.|.:.:||  ||......:.|.|
Mouse   270 ERTRSMLLFANVSARH-----YGNYTCRAANRLGASSASMRL--LRPGSLENSAPRP 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-lambdaNP_001334747.1 None
Iglon5NP_001157990.1 Ig 41..129 CDD:416386 26/92 (28%)
Ig strand A' 41..46 CDD:409353 3/4 (75%)
Ig strand B 48..56 CDD:409353 1/7 (14%)
CDR1 56..60 CDD:409353 1/5 (20%)
FR2 61..68 CDD:409353 4/6 (67%)
Ig strand C 61..67 CDD:409353 4/5 (80%)
CDR2 69..79 CDD:409353 2/11 (18%)
Ig strand C' 71..74 CDD:409353 2/2 (100%)
Ig strand C' 76..79 CDD:409353 0/2 (0%)
FR3 80..115 CDD:409353 9/34 (26%)
Ig strand D 84..91 CDD:409353 1/6 (17%)
Ig strand E 94..100 CDD:409353 0/5 (0%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 1/3 (33%)
Ig strand G 120..129 CDD:409353 3/9 (33%)
FR4 122..129 CDD:409353 2/6 (33%)
Ig strand A 132..137 CDD:409353 2/4 (50%)
Ig_3 134..199 CDD:404760 28/82 (34%)
Ig strand A' 140..145 CDD:409353 1/6 (17%)
Ig strand B 148..157 CDD:409353 3/8 (38%)
Ig strand C 163..167 CDD:409353 1/3 (33%)
Ig strand D 174..177 CDD:409353 1/3 (33%)
Ig strand E 178..183 CDD:409353 2/4 (50%)
Ig strand F 191..199 CDD:409353 3/7 (43%)
Ig_3 217..295 CDD:404760 16/83 (19%)
putative Ig strand A 218..224 CDD:409353 2/5 (40%)
Ig strand B 234..238 CDD:409353 1/3 (33%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 0/3 (0%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Ig strand G 301..304 CDD:409353 0/2 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 45 1.000 Domainoid score I12107
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4449
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8732
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
76.970

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