DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NimB2 and SCARF2

DIOPT Version :9

Sequence 1:	NP_723857.1	Gene:	NimB2 / 260645	FlyBaseID:	FBgn0028543	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_699165.3	Gene:	SCARF2 / 91179	HGNCID:	19869	Length:	871	Species:	Homo sapiens

Alignment Length:	389	Identity:	84/389 - (21%)
Similarity:	117/389 - (30%)	Gaps:	159/389 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 SRIQVCCDGYERNPHIYRRCEPICADDCRNGICTAPNTC----VCI-PGHVRTAEG----KCIST 217
            |::..||.|:.:.           .|:|...:|...:||    ||: ||..|...|    .|.:.
Human    59 SQVPTCCAGWRQQ-----------GDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTK 112

  Fly   218 CP-----------------------------------------LGCGNGVCDERN-ECKCREG-Y 239
            ||                                         ..|.:|.|..|: .|:|..| :
Human   113 CPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWW 177

  Fly   240 SLEPETRKYCQ--PECKPGCSFGRCV---------APNKCACLDGYRLAADGSCE-------PVC 286
            ..:..:..||.  ..|.|  ..|.|:         ..|:|||.........|.|:       ..|
Human   178 GAQCASACYCSATSRCDP--QTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARC 240

  Fly   287 D---SCENGKC-TAPGHCNCNAGYLKLQGRCEPICSIPC-----------KNGRCIGPDICECAS 336
            |   .|..|:| ...|.|.|..||   :|:   .|..||           :.|:|.|...|..|.
Human   241 DRYCQCFRGRCHPVDGTCACEPGY---RGK---YCREPCPAGFYGLGCRRRCGQCKGQQPCTVAE 299

  Fly   337 GFEWDRKSAECLP-----KCDLPCLNGV-----------CVGNNQCD--------CKTGYVRDEH 377
            |     :...|.|     |||.||..|.           |...:.|:        |..|::.|.
Human   300 G-----RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR- 358

  Fly   378 QRNICQPHCPQG------------CQNGYCS-APNFCICRPGF--------IKSGIKGRQTCQA 420
                |:..|..|            |.:|:|. ....|:|.||.        ...|:.|....||
Human   359 ----CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
NimB2	NP_723857.1	None
SCARF2	NP_699165.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		PHA03247	<534..871	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	570..871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900