DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB2 and Creld2

DIOPT Version :9

Sequence 1:	NP_723857.1	Gene:	NimB2 / 260645	FlyBaseID:	FBgn0028543	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_083996.1	Gene:	Creld2 / 76737	MGIID:	1923987	Length:	350	Species:	Mus musculus

Alignment Length:	228	Identity:	63/228 - (27%)
Similarity:	85/228 - (37%)	Gaps:	79/228 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 IQVCCDGYERNPHIYRRCEPICADDCR---------NGICTAPNTCVCIPGHVRTAEGKCISTCP 219
            ::.||     .|..|   .|.| .:|:         ||.|:...:        |..:|.|  .|.
Mouse   122 LKACC-----LPGTY---GPDC-QECQGGSERPCSGNGYCSGDGS--------RQGDGSC--QCH 167

  Fly   220 LGCGNGVCDERNECKCREG-YSLE-PETRKYCQPECKPGCSFGRCVAPN-----KC--------- 268
            .|....:|.:     |.:| :||: .||...|. .|...|.  .|..|:     :|
Mouse   168 TGYKGPLCID-----CTDGFFSLQRNETHSICS-ACDESCK--TCSGPSNKDCIQCEVGWARVED 224

  Fly   269 ACLDGYRLAADGS-------CEPV-----CDSCENG--KCTAPGHCNCN---AGYLKLQGRCEPI 316
            ||:|....||:.|       ||.|     |:.|::.  .||..|..||.   |||.|..|:|..|
Mouse   225 ACVDVDECAAETSPCSDGQYCENVNGSYTCEDCDSTCVGCTGKGPANCKECIAGYTKESGQCTDI 289

  Fly   317 --CSI---PC--KNGRCI---GPDICECASGFE 339
              ||:   .|  ||..|.   |..:|.|..|||
Mouse   290 DECSLEEKACKRKNENCYNVPGSFVCVCPEGFE 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB2	NP_723857.1	None
Creld2	NP_083996.1	CXXC. /evidence=ECO:0000305\|PubMed:23956175	29..32
		FU 1	191..238		11/49 (22%)
		FU	196..246	CDD:238021	11/51 (22%)
		FU 2	251..298		16/46 (35%)
		FU	253..288	CDD:214589	13/34 (38%)
		CXXC. /evidence=ECO:0000305\|PubMed:23956175	261..264		0/2 (0%)
		vWFA	<286..326	CDD:381780	14/37 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000