DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB2 and Esm1

DIOPT Version :9

Sequence 1:	NP_723857.1	Gene:	NimB2 / 260645	FlyBaseID:	FBgn0028543	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_076101.1	Gene:	Esm1 / 71690	MGIID:	1918940	Length:	184	Species:	Mus musculus

Alignment Length:	153	Identity:	38/153 - (24%)
Similarity:	48/153 - (31%)	Gaps:	62/153 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 CDGYERNPHIYRRCEPICADDCRNGICTAPNTCVCIPGHV--RTAEGKCISTCPLGCGNGVCDER 230
            ||..|....:  ||:....|||  |.|   ..|...||..  ||..|    ...:.||.|:
Mouse    32 CDKTECRSSL--RCKRTVLDDC--GCC---QVCAAGPGETCYRTVSG----MDGVKCGPGL---- 81

  Fly   231 NECKCREGYSLEPETRKYCQPECKPGCSFGRCVAPNKCACLDGYRLAADGSCEPVCDSCENG--- 292
               || ..||.|.:.          |..||                        :|..|..|
Mouse    82 ---KC-HFYSEEDDF----------GDEFG------------------------ICKDCPYGTFG 108

  Fly   293 -KCTAPGHCNCNAGYL-KLQGRC 313
             :|...  |||.:|.. ::.|||
Mouse   109 MECKET--CNCQSGICDRVTGRC 129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB2	NP_723857.1	None
Esm1	NP_076101.1	IGFBP	28..83	CDD:278641	19/68 (28%)
Esm1	NP_076101.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..184
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900