Protein Alignment NimB2 and TNC

DIOPT Version :9

• Sequence 1: NP_723857.1
• Gene: NimB2 / 260645
• FlyBaseID: FBgn0028543
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: XP_016870167.1
• Gene: TNC / 3371
• HGNCID: 5318
• Length: 2384
• Species: Homo sapiens
• Alignment Length: 465
• Identity: 116/465 - (24%)
• Similarity: 157/465 - (33%)
• Gaps: 178/465 - (38%)

  Fly    18 CSLGQGQFKTAGIKTRQPPSGNLQLAGNSSESGWRSYNQS---------------------SYGW 61
            || |:|.|.|.|             .|...|.||:..|.|                     ..|:
Human   161 CS-GRGNFSTEG-------------CGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGF 211

  Fly    62 STQNQSNYA----WNQQNHVEQGSA----GFVRAEVFQPVTLPPLYGHYVQPVTPPAHRVQVLDE 118
            :.::.|..|    .|.|.....|..    |:..|:..:.:...|
Human   212 TGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVP--------------------- 255

  Fly   119 TALFINKTRSAMASGVCYKEVPTASLLRNSRDQFVGNGTTPDMSRIQVCCDGYERNPHIYRRC-E 182
                            |.:|                :||..|  .:.||.||:..:.     | :
Human   256 ----------------CSEE----------------HGTCVD--GLCVCHDGFAGDD-----CNK 281

  Fly   183 PICADDCRN-GICTAPNTCVCIPGHVRTAE--------------GKCIS---------------- 216
            |:|.::|.| |.| ..|.|||..|.  |.|              |:||:
Human   282 PLCLNNCYNRGRC-VENECVCDEGF--TGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGK 343

  Fly   217 -TCPLGC-GNGVCDERNECKCREGYSLEPETRKYCQPECKPGCSFGRCVAPNKCACLDGYRLAAD 279
             |||..| ..|.|:| .:|.|.||::....:.|.|..:|.   :.|||| ..:|.|.||:..|..
Human   344 PTCPHACHTQGRCEE-GQCVCDEGFAGVDCSEKRCPADCH---NRGRCV-DGRCECDDGFTGADC 403

  Fly   280 G--SCEPVCDSCENGKCTAPGHCNCNAGYLK---LQGRCEPICSIPCKNGRCIGPDICECASGFE 339
            |  .|...|..  :|:| ..|.|.|:.||..   .|.||...|.   ..|||: ...|.|..||
Human   404 GELKCPNGCSG--HGRC-VNGQCVCDEGYTGEDCSQLRCPNDCH---SRGRCV-EGKCVCEQGF- 460

  Fly   340 WDRKSAECLPKCDLPCLN-----GVCVGNNQCDCKTGYVRDEHQRNICQP-HCPQGCQN-GYCSA 397
               |..:|   .|:.|.|     |.|| |..|.|..||..::     |:. .||:.|.| |.| .
Human   461 ---KGYDC---SDMSCPNDCHQHGRCV-NGMCVCDDGYTGED-----CRDRQCPRDCSNRGLC-V 512

  Fly   398 PNFCICRPGF 407
            ...|:|..||
Human   513 DGQCVCEDGF 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimB2	NP_723857.1	None
TNC	XP_016870167.1	EGF_2	377..403	CDD:285248	11/29 (38%)
		EGF_2	408..434	CDD:285248	9/28 (32%)
		EGF_2	468..496	CDD:285248	10/33 (30%)
		EGF_2	504..527	CDD:285248	8/20 (40%)
		EGF_2	533..558	CDD:285248
		fn3	624..695	CDD:306538
		fn3	713..793	CDD:306538
		fn3	804..884	CDD:306538
		fn3	894..976	CDD:306538
		fn3	986..1064	CDD:306538
		fn3	1075..1154	CDD:306538
		fn3	1169..1241	CDD:306538
		fn3	1260..1327	CDD:306538
		fn3	1348..1427	CDD:306538
		fn3	1439..1508	CDD:306538
		fn3	1533..1605	CDD:306538
		fn3	1619..1691	CDD:306538
		fn3	1716..1788	CDD:306538
		fn3	1804..1883	CDD:306538
		fn3	1894..1973	CDD:306538
		fn3	1985..2055	CDD:306538
		fn3	2071..2143	CDD:306538
		Fibrinogen_C	2163..2372	CDD:278572

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910