DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB2 and Scarf2

DIOPT Version :9

Sequence 1:	NP_723857.1	Gene:	NimB2 / 260645	FlyBaseID:	FBgn0028543	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_036015777.1	Gene:	Scarf2 / 224024	MGIID:	1858430	Length:	838	Species:	Mus musculus

Alignment Length:	393	Identity:	89/393 - (22%)
Similarity:	122/393 - (31%)	Gaps:	160/393 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 TPDMSRIQVCCDGYERNPHIYRRCEPICADDCRNGICTAPNTC----VCI-PGHVRTAEG----K 213
            ||. |::..||.|:.:           ..|:|...:|...:||    ||: ||..|...|    .
Mouse    48 TPG-SQVLTCCAGWRQ-----------LGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGAN 100

  Fly   214 CISTCPLGCGNGVCDERNECKCREGYSLEPET-------RKY--------------CQP-----E 252
            |.:.||.......|.||  |.|......|..|       |::              |.|     .
Mouse   101 CDTKCPRQFWGPDCKER--CSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACR 163

  Fly   253 CKPG-----------CS--------FGRCV---------APNKCACLDGYRLAADGSCE------ 283
            |:||           ||        .|.|:         ..|:|||.........|.|:
Mouse   164 CEPGWWGAQCASACYCSATSRCDPQTGACLCHVGWWGRSCNNQCACNSSPCEQQSGRCQCRERMF 228

  Fly   284 -PVCD---SCENGKC-TAPGHCNCNAGYLKLQGRCEPICSIPC-----------KNGRCIGPDIC 332
             ..||   .|.:|:| ...|.|.|:.||   :|:   .|..||           :.|:|.|...|
Mouse   229 GARCDRYCQCSHGRCHPVDGTCACDPGY---RGK---YCREPCPAGFYGPGCRRRCGQCKGQQPC 287

  Fly   333 ECASGFEWDRKSAECLP-----KCDLPCLNGV-----------CVGNNQCD--------CKTGYV 373
            ....|     :...|.|     |||.||..|.           |...:.|:        |..|::
Mouse   288 TVVEG-----RCLTCEPGWNGTKCDQPCATGFYGEGCGHRCPPCRDGHACNHVTGKCTHCNAGWI 347

  Fly   374 RDEHQRNICQPHCPQG------------CQNGYCS-APNFCICRPGF--------IKSGIKGRQT 417
            .|.     |:..|..|            |.:|:|. ....|:|.||.        ..:|:.|...
Mouse   348 GDR-----CETKCSNGTYGEDCAFVCSDCGSGHCDFQSGRCLCSPGVHGPHCNVTCPAGLHGVDC 407

  Fly   418 CQA 420
            .||
Mouse   408 AQA 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB2	NP_723857.1	None
Scarf2	XP_036015777.1	exchanger_TraA	<74..431	CDD:411343	80/355 (23%)
		PHA03307	526..>836	CDD:223039
		PHA03247	<683..838	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900