DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB2 and Tnr

DIOPT Version :9

Sequence 1:	NP_723857.1	Gene:	NimB2 / 260645	FlyBaseID:	FBgn0028543	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_071707.2	Gene:	Tnr / 21960	MGIID:	99516	Length:	1358	Species:	Mus musculus

Alignment Length:	404	Identity:	98/404 - (24%)
Similarity:	137/404 - (33%)	Gaps:	147/404 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 ESGWRSYNQSSYGWSTQNQS---NYAWNQQNHVEQGSAGFVRAEVFQPVTLPPLYGHYVQPVTPP 109
            |.|..|||.||     :.|.   |:.:|....:|...:..:.|...|.::...
Mouse    48 EGGASSYNTSS-----KEQPMVFNHVYNINVPLESLCSSGLEASAEQDMSAED------------ 95

  Fly   110 AHRVQVLDETALFINKTRSAMASGVCY--------KEVPTASLLRNSRDQFVGNGTTPDMSRIQV 166
                   |..|.:|.:| |...|.|.:        |..|.||..:..::.         :|||::
Mouse    96 -------DTLAEYIGQT-SDHESQVTFTHKINLPKKACPCASSSQVLQEL---------LSRIEM 143

  Fly   167 CCDGYERNPHIYRRCEPICADDCRNGICTAPNTCVCIPGHVRTAEGKCISTCPLGCGNGVCDERN 231
                .||...:.|       |.|....|..         ...|.:...:..|. |.|| ...|..
Mouse   144 ----LEREVSLLR-------DQCNTNCCQE---------SAATGQLDYVPHCS-GHGN-FSFESC 186

  Fly   232 ECKCREGYSLEPETRKYC-QPECKPGCSF-GRCVAPNKCACLDGYRLAADGSCEPVCDS------ 288
            .|.|.||:     ..|.| :|.|..|||. |.||               ||.|  :|||
Mouse   187 GCICNEGW-----FGKNCSEPYCPLGCSSRGVCV---------------DGQC--ICDSEYSGDD 229

  Fly   289 CENGKCTAPGHCNCNAGYLKLQGRC---EPICSIPCKNGRCIGPDICECASGFEWDRKSAECLPK 350
            |...:|..    :|::..|.:.|.|   ||.....|:..||.|                 :|..|
Mouse   230 CSELRCPT----DCSSRGLCVDGECVCEEPYTGEDCRELRCPG-----------------DCSGK 273

  Fly   351 CDLPCLNGVCVGNNQCDCKTGYV-RDEHQR---NIC--QPHCPQG---CQNGY----CSAPNFCI 402
            ..  |.||.|:      |:.||. .|..||   |.|  :.||.:|   |:.||    |||    :
Mouse   274 GQ--CANGTCL------CQEGYAGEDCSQRRCLNACSGRGHCQEGLCICEEGYQGPDCSA----V 326

  Fly   403 CRPGFIK-SGIKGR 415
            ..|..:: :||..|
Mouse   327 APPEDLRVAGISDR 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB2	NP_723857.1	None
Tnr	NP_071707.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	37..58		5/9 (56%)
		exchanger_TraA	<190..>328	CDD:411343	54/192 (28%)
		EGF_Tenascin	203..231	CDD:376143	13/44 (30%)
		fn3	328..398	CDD:394996	4/13 (31%)
		fn3	416..496	CDD:394996
		fn3	507..586	CDD:394996
		FN3	595..679	CDD:238020
		fn3	687..766	CDD:394996
		fn3	776..855	CDD:394996
		fn3	865..944	CDD:394996
		fn3	954..1026	CDD:394996
		FN3	1042..1127	CDD:238020
		FBG	1134..1343	CDD:214548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910