Protein Alignment CNTNAP2 and LYS5

DIOPT Version :10

• Sequence 1: NP_054860.1
• Gene: CNTNAP2 / 26047
• HGNCID: 13830
• Length: 1331
• Species: Homo sapiens
• Sequence 2: NP_011361.1
• Gene: LYS5 / 852723
• SGDID: S000003122
• Length: 272
• Species: Saccharomyces cerevisiae
• Alignment Length: 264
• Identity: 54/264 - (20%)
• Similarity: 90/264 - (34%)
• Gaps: 77/264 - (29%)

Human   232 QGDYITLELKKAKLVLSLNLGS------------------NQLGPIYGHTSVMTG---------- 268
            |.|.:..|.....|:.:|.|.|                  :||..::| .|::||
Yeast    29 QEDILADEFTFEALMRTLPLASQARILNKKSFHDRCSNLCSQLLQLFG-CSIVTGLNFQELKFDK 92

Human   269 -----SLLDDHHW--HSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPS 326
                 ..||::.:  .|:.|..|..::.|....|...::..|    :|:.....:||
Yeast    93 GSFGKPFLDNNRFLPFSMTIGEQYVAMFLVKCVSTDEYQDVG----IDIASPCNYGG-------- 145

Human   327 SSSRKNFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVFFNATSYLEVPGRLN 391
            ....:.||.......:||:       .|..:|..:....:|..|.||.   |..|.       ||
Yeast   146 REELELFKEVFSEREFNGL-------LKASDPCTIFTYLWSLKESYTK---FTGTG-------LN 193

Human   392 QDLFSVSFQFRTWNP-NGL----------LVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQI 445
            .||..:.|...::.| .|.          |:|.....|...|.|.:.:| :...||..:.|:..|
Yeast   194 TDLSLIDFGAISFFPAEGASMCITLDEVPLIFHSQWFNNEIVTICMPKS-ISDKINTNRPKLYNI 257

Human   446 DISS 449
            .:|:
Yeast   258 SLST 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNTNAP2	NP_054860.1	FA58C	<70..180	CDD:238014
		Laminin_G_2	216..345	CDD:460494	27/147 (18%)
		LamG	375..527	CDD:238058	20/86 (23%)
		EGF_CA	555..590	CDD:238011
		GGGWT_bact	598..634	CDD:468872
		LamG	800..943	CDD:238058
		EGF	967..>992	CDD:394967
		Laminin_G_2	1055..1187	CDD:460494
		4.1m	1282..1300	CDD:128590
LYS5	NP_011361.1	Sfp	32..197	CDD:441694	37/194 (19%)