Protein Alignment SETBP1 and set-21

DIOPT Version :9

• Sequence 1: XP_024306917.1
• Gene: SETBP1 / 26040
• HGNCID: 15573
• Length: 1622
• Species: Homo sapiens
• Sequence 2: NP_500555.2
• Gene: set-21 / 177204
• WormBaseID: WBGene00021282
• Length: 568
• Species: Caenorhabditis elegans
• Alignment Length: 531
• Identity: 95/531 - (17%)
• Similarity: 176/531 - (33%)
• Gaps: 151/531 - (28%)

Human   223 LPQDFTGDTLKPKHQQKSSSQNHMDWSTNSDSGPVTQNCFISPESGRETASTSKIPALEPVASFA 287
            :|.|  .:.||.|.|::|..:|. |.|:|:             |..|:.:...::|..:..|.:.
 Worm     1 MPVD--AEKLKSKAQKRSIGEND-DKSSNA-------------EPPRKRSKAMRLPTDDEDAKYV 49

Human   288 KAQG--KKGSAGNTWSQLSNNNKDLLLGGVAPSPSS--------HSSPAPPSSSAECNGLQPLVD 342
            :.:.  ||.||..|...|    :.:.....|| |..        :||....|....|.    |:.
 Worm    50 ETKRALKKYSADKTSEML----RVIKFAFKAP-PFKLELPVYLRYSSYQLSSYRDRCQ----LLK 105

Human   343 QDGGGTKEPPEPPTVGSKKKSSKKDVISQTIPNPDLDWVKNAQKAFDNTEGKREG---------- 397
            .:...|:...||..:   ..::..:::.:...:|:|    |....:..||.|..|
 Worm   106 DNSELTRINVEPNII---TLNAHLNLLERIRDDPEL----NTYYEYQETENKDLGRCMRFIAQRI 163

Human   398 ---YSADSAQEASPARQNVSSASNPENDSSHVRITIPIKAPSLDPTNHKRKKRQSIKAVVEKIMP 459
               .:.::..:...|.|..|:...||:...:.        |:.:|..::.:.:.::......::|
 Worm   164 VMARTNNNLMKHLLAEQGTSTEITPESLQEYF--------PAYEPPKNRIRIKSNLTFNENDVIP 220

Human   460 EKALASGITMSSEVVNRILS------NSEGNKKDPRVPKLSKMIENESPSVGLETGGNAEKVIP- 517
            ..:...|.|:.|..:...|:      |......:|.:.|...|.|....::...|..:::.::|
 Worm   221 VYSDLEGETLESLEIPVTLTYDYTDVNMVDQFTEPNLTKAIIMSEENGENMIRCTCCSSKPIVPC 285

Human   518 ---------------GGVSKPR-----------KPPMVMTPPTCTDHSPSRKLPEIQHPKFAAKR 556
                           .|...||           ||.....|   .||       ...|..||...
 Worm   286 YENEKCPCFIMNQRMQGFQIPREGCGKTEFTSFKPIYFFNP---KDH-------YYDHAGFACSE 340

Human   557 RWTCSKPKPSTMLREAVMATSDKLMLEPPSAYPITPSSPLYTNTDSLTVITPVKKKRGRPKKQPL 621
            ...|..           ..|::.::|.....:|:    .:|.|..::..:  |:.....|...||
 Worm   341 LCGCGG-----------KCTNNSMLLPHKKLFPL----EIYRNDPAVGFV--VRSTVMIPAGTPL 388

Human   622 LTVETIHEGTSTSPVSPISREFPG---TKKRKRRRNLAKLAQLVPGED----KPMSEMKFHKKVG 679
            :                   ||.|   ..|.....|.....|:...:|    :.:.|:||.|:..
 Worm   389 M-------------------EFTGEIVELKNMELDNRDYAYQITYSDDVKFRRLLQEVKFSKEYT 434

Human   680 KLGVLDKKTIK 690
            ||  |:|.:.|
 Worm   435 KL--LEKLSRK 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SETBP1	XP_024306917.1	None
set-21	NP_500555.2	SET	<336..503	CDD:394802	28/146 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161469981
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930