Protein Alignment L3MBTL1 and L3mbtl1

DIOPT Version :10

• Sequence 1: NP_001364232.1
• Gene: L3MBTL1 / 26013
• HGNCID: 15905
• Length: 862
• Species: Homo sapiens
• Sequence 2: XP_011237842.1
• Gene: L3mbtl1 / 241764
• MGIID: 2676663
• Length: 848
• Species: Mus musculus
• Alignment Length: 812
• Identity: 651/812 - (80%)
• Similarity: 704/812 - (86%)
• Gaps: 22/812 - (2%)

Human     1 MEGHAEMEMLRTLKGPSTGEVSMHLVAGDSPGSGPHLPATAFIIPASSATLGLPSSALDVSCFPR 65
            ||||.:||:|||:||.|||||::||||.||.|..|.||.||||||.::|||||||:||||. :||
Mouse     1 MEGHTDMEILRTVKGSSTGEVNVHLVARDSAGPHPQLPTTAFIIPTNAATLGLPSTALDVP-YPR 64

Human    66 EPIHVGAPEQVAGCEPVSATVLPQLSAGPASSSTSTVRLLEWTEAAAPPPGGGLRFRISEYKPLN 130
            ||:||||.|:|||.|||:||:|||||.|  :.:.||||||:||..:||.||.|:||||:||.|||
Mouse    65 EPVHVGALERVAGSEPVTATILPQLSTG--TGTNSTVRLLDWTGVSAPLPGSGMRFRINEYAPLN 127

Human   131 MAGVEQPPSPELRQEGVTEYEDGGAPAGDGEAGPQQAEDHPQNPPEDPNQDPPEDDSTCQCQACG 195
            |.|||:|.|||.|.||.....|         ||.|..:.| |:..:..:.:||.|.|:|:|||||
Mouse   128 MIGVERPRSPEQRHEGGMARRD---------AGIQHPDVH-QDRQDITSLEPPVDASSCKCQACG 182

Human   196 PHQAAGPDLGSSNDGCPQLFQERSVIVENSSGSTSASELLKPMKKRKRREYQSPSEEESEPEAME 260
            |.|::|.|:|||.|.|.|.||:||||||| ||.|.||||||||||||.:|||||| |||||||:
Mouse   183 PQQSSGLDVGSSGDRCSQPFQKRSVIVEN-SGCTIASELLKPMKKRKHKEYQSPS-EESEPEAV- 244

Human   261 KQEEGKDPEGQPTASTPESEEWSSSQPATGEKKECWSWESYLEEQKAITAPVSLFQDSQAVTHNK 325
            ||.||||.|.:||.||||:||||.||..:.|||:.||||||||||||:|||||||||||||||||
Mouse   245 KQGEGKDAEREPTPSTPENEEWSRSQLVSSEKKDGWSWESYLEEQKAVTAPVSLFQDSQAVTHNK 309

Human   326 NGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTG 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   310 NGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTG 374

Human   391 HKLQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVA 455
            ||||.||||||||||||||||||:|||||||||||||||.||:||||||||||||||||||||||
Mouse   375 HKLQLPKGYKEEEFSWSQYLRSTKAQAAPKHLFVSQSHSTPPVGFQVGMKLEAVDRMNPSLVCVA 439

Human   456 SVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEE 520
            |||||||||||||||:|.|||||||||||||||||||||||||||||||||||||:|||||||||
Mouse   440 SVTDVVDSRFLVHFDDWGDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDSFCWEKYLEE 504

Human   521 TGASAVPTWAFKVRPPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWID 585
            ||.||||.||||||||||||||||||||||||||||||||||||||||||:|||||||.||||||
Mouse   505 TGTSAVPNWAFKVRPPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKLHFDGWSHNYDFWID 569

Human   586 ADHPDIHPAGWCSKTGHPLQPPLGPREPSSASPGGCPPLSYRSLPHTRTSKYSFHHRKCPTPGCD 650
            |||||||||||||||||||:|||.|||.||.|||||||||:||.|||:||||:||||||||||||
Mouse   570 ADHPDIHPAGWCSKTGHPLEPPLRPRESSSVSPGGCPPLSHRSPPHTKTSKYNFHHRKCPTPGCD 634

Human   651 GSGHVTGKFTAHHCLSGCPLAERNQSRLKAELSDSEASARKKNLSGFSPRKKPRHHGRIGRPPKY 715
            ||||||||||||||||||||||:|||||||||||||.:|||||.|..||||||||.|||||||||
Mouse   635 GSGHVTGKFTAHHCLSGCPLAEKNQSRLKAELSDSETAARKKNPSNLSPRKKPRHQGRIGRPPKY 699

Human   716 RKIPQEDFQTLTPDVVHQSLFMSALSAHPDRSLSVCWEQHCKLLPGVAGISASTVAKWTIDEVFG 780
            ||||:||.|.|.|.|||||||||.|..|.||.|||||||||||||||||||||||:||||:||||
Mouse   700 RKIPEEDLQALPPSVVHQSLFMSTLPTHADRPLSVCWEQHCKLLPGVAGISASTVSKWTIEEVFG 764

Human   781 FVQTLTGCEDQARLFKDEA------RIVRVTH 806
            |||||||.||||||||||.      |.:|.||
Mouse   765 FVQTLTGSEDQARLFKDEQATEEEHRGLRTTH 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
L3MBTL1	NP_001364232.1	PRK07764	<27..188	CDD:236090	89/160 (56%)
		MBT_L3MBTL1_rpt1	315..423	CDD:439121	105/107 (98%)
		MBT_L3MBTL1_rpt2	430..522	CDD:439124	86/91 (95%)
		MBT_L3MBTL1_rpt3	535..609	CDD:439127	70/73 (96%)
		zf-C2HC	643..671	CDD:460240	27/27 (100%)
		SAM_superfamily	770..>798	CDD:472832	24/27 (89%)
L3mbtl1	XP_011237842.1	MBT_L3MBTL1_rpt1	299..407	CDD:439121	105/107 (98%)
		MBT_L3MBTL1_rpt2	414..506	CDD:439124	86/91 (95%)
		MBT_L3MBTL1_rpt3	519..593	CDD:439127	70/73 (96%)
		zf-C2HC	627..655	CDD:460240	27/27 (100%)
		SAM_superfamily	754..>787	CDD:472832	26/32 (81%)