DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RNF167 and DMA1

DIOPT Version :9

Sequence 1:	NP_001357232.1	Gene:	RNF167 / 26001	HGNCID:	24544	Length:	374	Species:	Homo sapiens
Sequence 2:	NP_011983.1	Gene:	DMA1 / 856515	SGDID:	S000001157	Length:	416	Species:	Saccharomyces cerevisiae

Alignment Length:	151	Identity:	38/151 - (25%)
Similarity:	62/151 - (41%)	Gaps:	39/151 - (25%)

- Green bases have known domain annotations that are detailed below.

Human   189 GAVMIARCIQHR------KRLQRNRLTKEQLKQIPTHDYQKALNSSMFCPDLILPTCLISSTGFV 247
            |...|.||::.:      .:|:.|...||.|.:|  .:.||.                  :||.
Yeast   279 GTEEIYRCVKMKIELNKSWKLKANAFNKEALSRI--KNLQKL------------------TTGL- 322

Human   248 GDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPW--LTQTRKTCPICKQPVHRGPGDEDQEE 310
             :|.| |:|||::.:....:.:.||||::|..||...  :...:..||.|:.       :.|.|.
Yeast   323 -EQED-CSICLNKIKPCQAIFISPCAHSWHFHCVRRLVIMNYPQFMCPNCRT-------NCDLET 378

Human   311 ETQGQEEGD-EGEPRDHPASE 330
            ..:.:.|.: |.|..|.|..|
Yeast   379 TLESESESEFENEDEDEPDIE 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RNF167	NP_001357232.1	PA_C_RZF_like	20..170	CDD:239038
		RING-H2_RNF167	252..297	CDD:319711	15/46 (33%)
		RING-H2 finger (C3H2C3-type)	254..295	CDD:319711	13/42 (31%)
DMA1	NP_011983.1	FHA	121..308	CDD:224630	7/28 (25%)
DMA1	NP_011983.1	RING-H2_Dmap_like	325..371	CDD:319372	14/46 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000