Protein Alignment CHMP2B and VPS24

DIOPT Version :10

• Sequence 1: NP_001397706.1
• Gene: CHMP2B / 25978
• HGNCID: 24537
• Length: 245
• Species: Homo sapiens
• Sequence 2: NP_012883.1
• Gene: VPS24 / 853825
• SGDID: S000001524
• Length: 224
• Species: Saccharomyces cerevisiae
• Alignment Length: 205
• Identity: 52/205 - (25%)
• Similarity: 101/205 - (49%)
• Gaps: 24/205 - (11%)

Human    47 KEQNRELRGTQR-------AIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQK 104
            |||.|.:|...|       ..:|:...|:.:.:||   |||.||..:....::.||:|..:.||.
Yeast    14 KEQQRRIRSVLRKNGRNIEKSLRELTVLQNKTQQL---IKKSAKKNDVRTVRLYAKELYQINKQY 75

Human   105 TRTFAVSSKVTSMSTQTKV-----MNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKEN 164
            .|.:  :|:....|.:.|:     ||:   ::..|:.:|..|:.||..:...:...||...:||.
Yeast    76 DRMY--TSRAQLDSVRMKIDEAIRMNT---LSNQMADSAGLMREVNSLVRLPQLRNTMIELEKEL 135

Human   165 MKMEMTEEMINDTLDDIFD-GSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSLPSASTSKA 228
            ||..:..||::||::.:.| |.:.:|...:.||:::::...|....:.:.|:...   :|:..:.
Yeast   136 MKSGIISEMVDDTMESVGDVGEEMDEAVDEEVNKIVEQYTNEKFKNVDQVPTVEL---AANEEEQ 197

Human   229 TISDEEIERQ 238
            .|.||:::.:
Yeast   198 EIPDEKVDEE 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHMP2B	NP_001397706.1	Snf7	48..217	CDD:460896	47/181 (26%)
VPS24	NP_012883.1	Snf7	19..189	CDD:460896	44/177 (25%)