Protein Alignment PARS2 and Pars2

DIOPT Version :10

• Sequence 1: NP_689481.2
• Gene: PARS2 / 25973
• HGNCID: 30563
• Length: 475
• Species: Homo sapiens
• Sequence 2: NP_001077356.1
• Gene: Pars2 / 230577
• MGIID: 2386296
• Length: 511
• Species: Mus musculus
• Alignment Length: 475
• Identity: 389/475 - (81%)
• Similarity: 427/475 - (89%)
• Gaps: 0/475 - (0%)

Human     1 MEGLLTRCRALPALATCSRQLSGYVPCRFHHCAPRRGRRLLLSRVFQPQNLREDRVLSLQDKSDD 65
            |||||||||.|.|||.||.:...|:..:.:|.||.||:||:|||:|||||||||:||||:.::.|
Mouse    37 MEGLLTRCRTLSALAACSLRHCRYIIHKCYHRAPGRGQRLVLSRMFQPQNLREDQVLSLEGRASD 101

Human    66 LTCKSQRLMLQVGLIYPASPGCYHLLPYTVRAMEKLVRVIDQEMQAIGGQKVNMPSLSPAELWQA 130
            |||||||||||||||.|||||||||:||||||:||||||||||||||||||:|||||||||||:|
Mouse   102 LTCKSQRLMLQVGLILPASPGCYHLMPYTVRAVEKLVRVIDQEMQAIGGQKINMPSLSPAELWRA 166

Human   131 TNRWDLMGKELLRLRDRHGKEYCLGPTHEEAITALIASQKKLSYKQLPFLLYQVTRKFRDEPRPR 195
            |:||||||:||||||||||||||||||||||:|||:||||||||||||.||||||||||||||||
Mouse   167 TSRWDLMGRELLRLRDRHGKEYCLGPTHEEAVTALVASQKKLSYKQLPLLLYQVTRKFRDEPRPR 231

Human   196 FGLLRGREFYMKDMYTFDSSPEAAQQTYSLVCDAYCSLFNKLGLPFVKVQADVGTIGGTVSHEFQ 260
            ||||||||||||||||||||.||||:||.|||||||.||::|||.::|.:||||:||||:|||||
Mouse   232 FGLLRGREFYMKDMYTFDSSSEAAQETYGLVCDAYCRLFDRLGLQWMKARADVGSIGGTMSHEFQ 296

Human   261 LPVDIGEDRLAICPRCSFSANMETLDLSQMNCPACQGPLTKTKGIEVGHTFYLGTKYSSIFNAQF 325
            ||||||||||.:||.|.||||.|.|||||..||.||||||:||||||||||||.|||||||||.|
Mouse   297 LPVDIGEDRLVVCPSCHFSANTEILDLSQKICPDCQGPLTETKGIEVGHTFYLSTKYSSIFNALF 361

Human   326 TNVCGKPTLAEMGCYGLGVTRILAAAIEVLSTEDCVRWPSLLAPYQACLIPPKKGSKEQAASELI 390
            ||..|:..|||||||||||||||||||||||||||:|||.||||||.|:|||||||||.||:|::
Mouse   362 TNAHGESLLAEMGCYGLGVTRILAAAIEVLSTEDCIRWPRLLAPYQVCVIPPKKGSKETAATEIV 426

Human   391 GQLYDHITEAVPQLHGEVLLDDRTHLTIGNRLKDANKFGYPFVIIAGKRALEDPAHFEVWCQNTG 455
            .:|||.|.||||||.||||||||||||||||||||||.||||||||||||||||||||||.||||
Mouse   427 EKLYDDIMEAVPQLRGEVLLDDRTHLTIGNRLKDANKLGYPFVIIAGKRALEDPAHFEVWSQNTG 491

Human   456 EVAFLTKDGVMDLLTPVQTV 475
            ||.||||:|||:|||.|..|
Mouse   492 EVVFLTKEGVMELLTGVHVV 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PARS2	NP_689481.2	ProRS_core_prok	65..354	CDD:238402	248/288 (86%)
		HGTP_anticodon	369..470	CDD:469699	84/100 (84%)
Pars2	NP_001077356.1	PRK09194	78..506	CDD:236405	362/427 (85%)