Protein Alignment GAPDH and CG9010

DIOPT Version :10

• Sequence 1: NP_002037.2
• Gene: GAPDH / 2597
• HGNCID: 4141
• Length: 335
• Species: Homo sapiens
• Sequence 2: NP_611172.1
• Gene: CG9010 / 36904
• FlyBaseID: FBgn0034173
• Length: 343
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 215/325 - (66%)
• Similarity: 248/325 - (76%)
• Gaps: 0/325 - (0%)

Human     6 VGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVIN 70
            :|:||||||||:..|.|.....|.|||||||.:|..|:.||.:||||||:|:..:..:...||:|
  Fly     4 IGINGFGRIGRMFARQALVRKDVKIVAINDPSLDPKYLAYMLRYDSTHGQFNQKISVDGNNLVVN 68

Human    71 GNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGV 135
            |..|.:.:|.|..||||.|.|...|||.:|.|||::....||..|||:|:||||||||||||.||
  Fly    69 GKKIQLLKESDVKKIKWCDLGVHTVVECSGRFTTLKACQGHLDSGAKKVVISAPSADAPMFVCGV 133

Human   136 NHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGR 200
            |.|.|.....||||||||||||||||||:||||.|.|||||||||.|||||.:||||.|||||||
  Fly   134 NLEAYKPGTAIISNASCTTNCLAPLAKVVHDNFEICEGLMTTVHAATATQKIIDGPSSKLWRDGR 198

Human   201 GALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQA 265
            ..:.||||||||||||||||||:|||||||||||||..|||||||||||.||||.|||||.:|.|
  Fly   199 SGMTNIIPASTGAAKAVGKVIPDLNGKLTGMAFRVPVPNVSVVDLTCRLSKPAKMDDIKKCIKAA 263

Human   266 SEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAH 330
            |:..:||||||.|.:|||:|||....:|.|||.|.|||||:|||||||||||.|||.|::||:.:
  Fly   264 SKCEMKGILGYVEEEVVSTDFNGSRFASVFDAKACIALNDNFVKLISWYDNETGYSCRLLDLVLY 328

Human   331  330
              Fly   329  328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPDH	NP_002037.2	PLN02272	2..332	CDD:177912	215/325 (66%)
		Interaction with WARS1. /evidence=ECO:0000269|PubMed:15628863	2..148		74/141 (52%)
		[IL]-x-C-x-x-[DE] motif. /evidence=ECO:0000305|PubMed:25417112	245..250		4/4 (100%)
CG9010	NP_611172.1	GapA	4..328	CDD:439827	215/323 (67%)