Protein Alignment GAPDH and Gapdh1

DIOPT Version :10

• Sequence 1: NP_002037.2
• Gene: GAPDH / 2597
• HGNCID: 4141
• Length: 335
• Species: Homo sapiens
• Sequence 2: NP_525108.2
• Gene: Gapdh1 / 35728
• FlyBaseID: FBgn0001091
• Length: 332
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 253/331 - (76%)
• Similarity: 288/331 - (87%)
• Gaps: 1/331 - (0%)

Human     5 KVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVI 69
            |:|:||||||||||.|||.:.| ..:||:||||||:|||||:|::|||||:|.|||.||.|.||:
  Fly     3 KIGINGFGRIGRLVLRAAIDKG-ASVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVV 66

Human    70 NGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMG 134
            ||..||:|.||||:.|.|..|||||||||||||||::||..||:||||:||||||||||||||.|
  Fly    67 NGQKITVFSERDPANINWASAGAEYVVESTGVFTTIDKASTHLKGGAKKVIISAPSADAPMFVCG 131

Human   135 VNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDG 199
            ||.:.|...:|::|||||||||||||||||:|||.|||||||||||.||||||||||||||||||
  Fly   132 VNLDAYSPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDG 196

Human   200 RGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQ 264
            |||.||||||:||||||||||||.||||||||||||||.||||||||.||.|.|.||:||..|::
  Fly   197 RGAAQNIIPAATGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGATYDEIKAKVEE 261

Human   265 ASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMA 329
            ||:||||||||||:.:|||:||.||||||.|||.|||:|||.||||||||||||||||||:||:.
  Fly   262 ASKGPLKGILGYTDEEVVSTDFFSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIK 326

Human   330 HMASKE 335
            :|.||:
  Fly   327 YMQSKD 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPDH	NP_002037.2	PLN02272	2..332	CDD:177912	250/326 (77%)
		Interaction with WARS1. /evidence=ECO:0000269|PubMed:15628863	2..148		97/142 (68%)
		[IL]-x-C-x-x-[DE] motif. /evidence=ECO:0000305|PubMed:25417112	245..250		3/4 (75%)
Gapdh1	NP_525108.2	PLN02272	<2..328	CDD:177912	250/325 (77%)