Protein Alignment TMEM87A and CG12121

DIOPT Version :10

• Sequence 1: NP_001425911.1
• Gene: TMEM87A / 25963
• HGNCID: 24522
• Length: 556
• Species: Homo sapiens
• Sequence 2: NP_572545.1
• Gene: CG12121 / 31866
• FlyBaseID: FBgn0030109
• Length: 738
• Species: Drosophila melanogaster
• Alignment Length: 379
• Identity: 71/379 - (18%)
• Similarity: 146/379 - (38%)
• Gaps: 83/379 - (21%)

Human   206 FTMTVEVKGPYEYLTLEDYPLMIFFMVMCIVYVLFGVLWLAWSACYWRDLLRIQFWIGAVIFLGM 270
            |.:.:|......||:..:.||...:.:|.:::.|.|:.|:.........:.:|.:.:..::||..
  Fly   408 FNVDIEENNNGNYLSAGEMPLPALYFMMSLLFFLSGLFWVFILKKSKHTVYKIHYLMAVLVFLKS 472

Human   271 LEKAVFYAEFQNIRYKGESVQGALILAELLSAVKRSLARTLVIIVSLGYGIVKPRLGVTLHKVVV 335
            |........:..|..:||.|:...||..:...:|.::....::::..|:..:|..|.....|:.:
  Fly   473 LSLMFHSINYHFIEKRGEHVETWAILYYIAHLLKGAVLFITIVLIGTGWTFIKHILSDKDKKIFM 537

Human   336 AGALYLLFSGMEGVLRVTGYFSYPLTLIVNLA------LSAIDACVILW----IFISLTQTMKLL 390
                                ...||.::.|:|      ....||....|    .|:.|.....:|
  Fly   538 --------------------IVIPLQVLANVAQIITDESDQSDAEFRTWHNIFFFVDLLCCGAIL 582

Human   391 ------------------KLRRNIVKLSLYRHFTNTLILAV--AASIVFIIWTTMKFRIVTCQSD 435
                              |...|:.||.|:|.|...::..:  ...||.::..|:.|:..
  Fly   583 FPIVWSIRHLHEASATDGKAAINLRKLKLFRQFYIMIVCYIYFTRIIVDLLQMTVVFQYA----- 642

Human   436 WRELWVDDAIWRLLFSMILFVIM-VLWRPSANNQRFAFSPLSEEEEEDEQKEPMLKESFEGMKMR 499
                |:|: ::|.:.:.:.||:. ..:||.:::..|.   :.:|:|:|::.| :|.||  |:
  Fly   643 ----WLDE-MFREMATYVFFVLTGYKFRPVSSHPYFT---VPDEDEDDDEVE-VLTES--GL--- 693

Human   500 STKQEPNGNSKVNKAQEDDLKWVEENVPSSVTDVALPALLDSDEERMITHFERS 553
                    ...|::     :|.:..|..|.:..:.:....|.:.|.:|...|.|
  Fly   694 --------TETVHR-----VKQLNRNHGSGLGGITIIEGNDDERENLIAKRESS 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM87A	NP_001425911.1	None
CG12121	NP_572545.1	LGT	<179..345	CDD:469786
		Lung_7-TM_R	387..671	CDD:369089	53/292 (18%)