| Sequence 1: | XP_011542783.1 | Gene: | ADGRA2 / 25960 | HGNCID: | 17849 | Length: | 1361 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001305000.1 | Gene: | adgra2 / 560700 | ZFINID: | ZDB-GENE-081104-363 | Length: | 1367 | Species: | Danio rerio |
| Alignment Length: | 1438 | Identity: | 706/1438 - (49%) |
|---|---|---|---|
| Similarity: | 887/1438 - (61%) | Gaps: | 155/1438 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Human 8 MRGAPARLLLPLLPWLLLLLAPEARGAPGCP-LSIRSCKCSGERPKGLSGGVPGPARRRVVCSGG 71
Human 72 DLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKR 136
Human 137 LDLSNNRIGCLTSETFQGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWL 201
Human 202 LPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLPF 266
Human 267 QCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGEWECTVS 331
Human 332 MAQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPG 396
Human 397 TRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMM 461
Human 462 DVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSRIVGALERIGGAA 526
Human 527 LSPHAQHISVNARNVALEAYLIKPHSYVGLTCTAFQRREGGVPGTRPGSPGQNPPPEPEPPADQQ 591
Human 592 LRFRCTTGRPNVSLSSFHIKNSVALASIQLPPSLFSSLPAALAPPVPPDCTLQLLVFRNGRLFHS 656
Human 657 HSNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGAEPVAAWWSQEGPGEA 721
Human 722 GGWTSEGCQLRSSQPNVSALHCQHLGNVAVLMELSAFPREVGGAGAGLHPVVYPCTALLLLCLFA 786
Human 787 TIITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLL 851
Human 852 WMGVKARVLHKELTWRAPPPQEGDPAL-PTPSPMLRYILSIPALQLGRDSNAGVGNLPRFYLIAG 915
Human 916 GIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILLITWIYFLCAGLRLRGPLAQN 980
Human 981 PKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSL---YSPGVQL 1042
Human 1043 GALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACC 1107
Human 1108 P---PASPAAPHAPP----RALPAAAEDGSPVF-GEGPP--------SLKSSPSGSSGHPLALGP 1156
Human 1157 CKLTN-LQLAQSQVCEAGAAAGGEGEPEPAGTRGNLAHRHPNN-------------VHHGRRAHK 1207
Human 1208 SRAKG-----HRAGEACGKNRLKALRGGAAGALELL-----------------SSESGSLHNSPT 1250
Human 1251 DSYLGSSRNSPGAGLQLEGEPMLT-PSEGSDTSAA------PL--SEAGRA-----GQRRSASRD 1301
Human 1302 SLKGGGALEKESHRRSYPLN-------AASLN--GAPKG---GKYDDVTLMGAEVASGGC-MKTG 1353
Human 1354 LWKSETTV 1361 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ADGRA2 | XP_011542783.1 | leucine-rich repeat | 86..109 | CDD:275378 | 15/22 (68%) |
| LRR_RI | <87..190 | CDD:238064 | 71/102 (70%) | ||
| LRR_8 | 88..144 | CDD:290566 | 39/55 (71%) | ||
| leucine-rich repeat | 110..133 | CDD:275378 | 19/22 (86%) | ||
| LRR_8 | 133..187 | CDD:290566 | 37/53 (70%) | ||
| leucine-rich repeat | 134..157 | CDD:275378 | 17/22 (77%) | ||
| leucine-rich repeat | 158..181 | CDD:275378 | 17/22 (77%) | ||
| leucine-rich repeat | 182..194 | CDD:275378 | 6/11 (55%) | ||
| LRRCT | 192..>227 | CDD:214507 | 15/34 (44%) | ||
| Ig | 257..343 | CDD:299845 | 48/85 (56%) | ||
| HRM | 351..417 | CDD:295297 | 42/65 (65%) | ||
| GPS | 708..752 | CDD:280071 | 19/43 (44%) | ||
| 7tm_4 | 778..>969 | CDD:304433 | 125/191 (65%) | ||
| adgra2 | NP_001305000.1 | leucine-rich repeat | 52..73 | CDD:275380 | 11/20 (55%) |
| LRR 1. /evidence=ECO:0000255 | 70..94 | 16/23 (70%) | |||
| leucine-rich repeat | 74..97 | CDD:275378 | 15/22 (68%) | ||
| LRR_8 | 76..132 | CDD:290566 | 39/55 (71%) | ||
| LRR_4 | 76..111 | CDD:289563 | 25/34 (74%) | ||
| LRR 2. /evidence=ECO:0000255 | 95..118 | 18/22 (82%) | |||
| LRR_4 | 97..137 | CDD:289563 | 30/39 (77%) | ||
| leucine-rich repeat | 98..121 | CDD:275378 | 19/22 (86%) | ||
| LRR 3. /evidence=ECO:0000255 | 119..142 | 15/22 (68%) | |||
| LRR_4 | 120..161 | CDD:289563 | 29/40 (73%) | ||
| LRR_8 | 122..174 | CDD:290566 | 36/51 (71%) | ||
| leucine-rich repeat | 122..145 | CDD:275378 | 17/22 (77%) | ||
| LRR 4. /evidence=ECO:0000255 | 144..166 | 15/21 (71%) | |||
| leucine-rich repeat | 146..169 | CDD:275378 | 17/22 (77%) | ||
| leucine-rich repeat | 170..182 | CDD:275378 | 6/11 (55%) | ||
| Ig_2 | 239..333 | CDD:290606 | 54/93 (58%) | ||
| IG_like | 241..333 | CDD:214653 | 53/91 (58%) | ||
| HRM | <355..405 | CDD:280888 | 32/49 (65%) | ||
| GAIN | 428..650 | CDD:293098 | 117/238 (49%) | ||
| GPS | 679..723 | CDD:280071 | 19/43 (44%) | ||
| 7tm_4 | 743..>925 | CDD:304433 | 132/204 (65%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 938..958 | 9/27 (33%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1126..1156 | 9/37 (24%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1221..1271 | 19/54 (35%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1339..1367 | 9/27 (33%) | |||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q96PE1 | 1364..1367 | 2/2 (100%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C194343831 | |
| Domainoid | 1 | 1.000 | 398 | 1.000 | Domainoid score | I4666 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BFVJ | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H13112 | |
| Inparanoid | 1 | 1.050 | 1212 | 1.000 | Inparanoid score | I1569 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG43535 | |
| OrthoDB | 1 | 1.010 | - | - | D21892at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0005128 | |
| OrthoInspector | 1 | 1.000 | - | - | oto45333 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104446 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR45930 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X3649 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| ZFIN | 1 | 1.500 | - | - | ||
| 17 | 17.270 | |||||