DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ATL3 and Atl3

DIOPT Version :9

Sequence 1:	NP_056274.3	Gene:	ATL3 / 25923	HGNCID:	24526	Length:	541	Species:	Homo sapiens
Sequence 2:	XP_006230874.1	Gene:	Atl3 / 309187	RGDID:	1309871	Length:	541	Species:	Rattus norvegicus

Alignment Length:	541	Identity:	508/541 - (93%)
Similarity:	522/541 - (96%)	Gaps:	0/541 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     1 MLSPQRVAAAASRGADDAMESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSV 65
            ||||||.||.|||||.||||:.||||||||||.|:||||||:|:||||:||||||||||||||||
  Rat     1 MLSPQRTAAVASRGAGDAMENGKPGPVQVVLVHKEQHSFELEERALASVLLQDHIRDLDVVVVSV 65

Human    66 AGAFRKGKSFILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEK 130
            ||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||:|
  Rat    66 AGAFRKGKSFILDFMLRYLYSQKEHGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVKK 130

Human   131 PGGKKVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRL 195
            |.||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 PCGKEVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRL 195

Human   196 AMDEIFQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIHSCFSDV 260
            ||||||||||||||||||||||||||:|||||||:||||||||||||||||||||||||||||||
  Rat   196 AMDEIFQKPFQTLMFLVRDWSFPYEYNYGLQGGMSFLDKRLQVKEHQHEEIQNVRNHIHSCFSDV 260

Human   261 TCFLLPHPGLQVATSPDFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGSKVTCRGLLEYF 325
            ||||||||||||||||||||||||||.|||||||.||||||||||||||||||||||||||||||
  Rat   261 TCFLLPHPGLQVATSPDFDGKLKDIASEFKEQLQTLIPYVLNPSKLMEKEINGSKVTCRGLLEYF 325

Human   326 KAYIKIYQGEDLPHPKSMLQATAEANNLAAAASAKDIYYNNMEEVCGGEKPYLSPDILEEKHCEF 390
            |||||||||||||||||||||||||||||||||||||||::|||:|||||||||||||||||.||
  Rat   326 KAYIKIYQGEDLPHPKSMLQATAEANNLAAAASAKDIYYSSMEEICGGEKPYLSPDILEEKHQEF 390

Human   391 KQLALDHFKKTKKMGGKDFSFRYQQELEEEIKELYENFCKHNGSKNVFSTFRTPAVLFTGIVALY 455
            |||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||..||
  Rat   391 KQLALDHFKKTKKMGGKDFSFRYQQELEEEITELYENFCKHNGSKNVFSTFRTPAVLFTGIAVLY 455

Human   456 IASGLTGFIGLEVVAQLFNCMVGLLLIALLTWGYIRYSGQYRELGGAIDFGAAYVLEQASSHIGN 520
            |||||||||||||||||||||||||||||||||||||||||.|||||||.|||||||||||||||
  Rat   456 IASGLTGFIGLEVVAQLFNCMVGLLLIALLTWGYIRYSGQYLELGGAIDSGAAYVLEQASSHIGN 520

Human   521 STQATVRDAVVGRPSMDKKAQ 541
            ||||.||||:.|||..|||:|
  Rat   521 STQAAVRDAIAGRPPADKKSQ 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATL3	NP_056274.3	P-loop_NTPase	37..305	CDD:304359	256/267 (96%)
Atl3	XP_006230874.1	P-loop_NTPase	37..305	CDD:304359	256/267 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83690955
Domainoid	1	1.000	524	1.000	Domainoid score	I6476
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9149
Inparanoid	1	1.050	1015	1.000	Inparanoid score	I5335
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG58971
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	1	1.000	-	-		FOG0001595
OrthoInspector	1	1.000	-	-		oto144025
orthoMCL	1	0.900	-	-		OOG6_102856
Panther	1	1.100	-	-	LDO	PTHR10751
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1147
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	17.370