Protein Alignment ATL3 and atln-1

DIOPT Version :9

• Sequence 1: NP_056274.3
• Gene: ATL3 / 25923
• HGNCID: 24526
• Length: 541
• Species: Homo sapiens
• Sequence 2: NP_001023492.1
• Gene: atln-1 / 177059
• WormBaseID: WBGene00021868
• Length: 573
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 285/518 - (55%)
• Similarity: 367/518 - (70%)
• Gaps: 15/518 - (2%)

Human    16 DDAMESSKPGPVQVVLVQKD-QHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKSFILDF 79
            :|.:...:|..|:||.|.:| .|||||:.:.|..|||...:.|..|.|:.||||:||||||:|:|
 Worm    22 EDVLLPKEPQAVRVVEVVEDTDHSFELNTELLEKILLDPKVADKKVAVIGVAGAYRKGKSFLLNF 86

Human    80 MLRYL---------YSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGKK 135
            .||||         ..:.|..:|.|: .|..||:||||||||:.:|.||.||||.|.::...|::
 Worm    87 FLRYLTWRSKADKVMGEVELDNSQWM-SPNSPLSGFSWRGGSERDTNGILIWSEPFIMKDKNGEE 150

Human   136 VAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRLAMDEI 200
            :||:||||||||||||||||||||||||||.||||||||||||||||||.|||||||||||:::.
 Worm   151 IAVLLMDTQGAFDSQSTVKDCATIFALSTMISSVQIYNLSQNIQEDDLQHLQLFTEYGRLALEDS 215

Human   201 FQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIHSCFSDVTCFLL 265
            ..||||:|:|||||||||||..:|.|||...||:||:|.|.||.|:|.:|.||.|||.|:.|||:
 Worm   216 ASKPFQSLLFLVRDWSFPYEAEFGFQGGQRVLDRRLEVSEKQHAELQQLRQHIRSCFEDIRCFLM 280

Human   266 PHPGLQVATSPDFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGSKVTCRGLLEYFKAYIK 330
            |||||:|||:|:|||||.||..||::||..:||.:|:...|:.|||||.|:|||.||||||||:.
 Worm   281 PHPGLKVATNPNFDGKLVDIENEFQQQLGVMIPRLLDSHALVHKEINGQKMTCRELLEYFKAYMH 345

Human   331 IYQGEDLPHPKSMLQATAEANNLAAAASAKDIYYNNMEEVCGGEKPYLSPDILEEKHCEFKQLAL 395
            |::|:|||.|||||.||||||||||.|||:.:|...|||||||:.||:|.:.|.|.|...|.:|:
 Worm   346 IFRGQDLPEPKSMLMATAEANNLAAVASARAVYQREMEEVCGGDTPYMSTNELLEHHDRVKNIAI 410

Human   396 DHFKKTKKMGGKDFSFRYQQELEEEIKELYENFCKHNGSKNVFSTFRTPAVLFTGIVALYIASGL 460
            ..|:..:||||.|||.::.:.||.:::|.|||:.|.|..||:|.:.|||.||.|.::..||....
 Worm   411 REFRNARKMGGVDFSMQFLERLESDLQESYENYLKVNNGKNLFKSMRTPTVLVTLMIIDYIFQEF 475

Human   461 TGFIGLEVVAQLFNCMVGLLLIALLTWGYIRYSGQYRELGGAIDFGAAYV----LEQASSHIG 519
            ...|||:.:|.|.:.::.|::.||..|.|.||||..||.||.:|....||    :...::|:|
 Worm   476 FQLIGLDFIAGLCSSVLCLVIGALGVWAYSRYSGHLREAGGYVDDAVTYVWTNFISPNANHLG 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATL3	NP_056274.3	P-loop_NTPase	37..305	CDD:304359	171/276 (62%)
atln-1	NP_001023492.1	P-loop_NTPase	43..325	CDD:393306	172/282 (61%)
		GBP_C	351..>447	CDD:308475	52/95 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161465717
Domainoid	1	1.000	356	1.000	Domainoid score	I552
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	567	1.000	Inparanoid score	I629
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58971
OrthoDB	1	1.010	-	-		D1027269at2759
OrthoFinder	1	1.000	-	-		FOG0001595
OrthoInspector	1	1.000	-	-		otm16380
orthoMCL	1	0.900	-	-		OOG6_102856
Panther	1	1.100	-	-	LDO	PTHR10751
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4011
SonicParanoid	1	1.000	-	-		X1147
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.940