Protein Alignment PAMR1 and CG9649

DIOPT Version :10

• Sequence 1: NP_056245.2
• Gene: PAMR1 / 25891
• HGNCID: 24554
• Length: 737
• Species: Homo sapiens
• Sequence 2: NP_650343.1
• Gene: CG9649 / 41727
• FlyBaseID: FBgn0038211
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 117/525 - (22%)
• Similarity: 186/525 - (35%)
• Gaps: 161/525 - (30%)

Human   273 NLLEAGKSKIKASEDSLSVLEERNCSDPGGPVNGYQKITGGPGL--------INGRHAKIGTVVS 329
            |.||        .||||     |:......|:| |:.....||:        :||:.|  ...|.
  Fly    78 NFLE--------DEDSL-----RHRLTNNEPIN-YRIDFPTPGVVPKLTKVTVNGKVA--CEAVP 126

Human   330 FFCNNSYVLSGNEKRTC----------QQNGEWSGKQPICIKACREPKISDLVRRRVLPMQVQSR 384
            |...::.:......||.          :.:.:|............|.:..:.|:|| .|.|..||
  Fly   127 FGAPSTRLSLSRTLRTSVPLAAIPPSQRTDHQWPQAPQTNYTVYEEEEEEEPVQRR-RPQQRPSR 190

Human   385 ETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPM-------GYQHLHTQLQYECISPFYRRLGSS 442
            ..|              |.||::....|...||.       ....:|........|.||.:
  Fly   191 PRP--------------QQAPSRPRLQPVPQLPQEPEFQTSARPSVHPSNTPAQASKFYPQ---- 237

Human   443 RRTCLRTGKWSGRAPSCIPICGKIENITAP------KTQGLRWPWQAAIYRRTSGVHDGSLHKGA 501
                 ..|:.||       |||:.:.|..|      :.:..:.||.||::.          |.|.
  Fly   238 -----TIGQLSG-------ICGREKVIQTPFIHNGIEVERGQLPWMAALFE----------HVGR 280

Human   502 -WFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVVLGKFYRDDDRD---EKTIQS----- 557
             :..:|.|.|::.|||:.||||                      :|...|:   |:||.|
  Fly   281 DYNFLCGGTLISARTVISAAHC----------------------FRFGSRNLPGERTIVSLGRNS 323

Human   558 ---------LQISAIILHPNYDP-ILLDADIAILKLLDKARISTRVQPICLAASRDLSTSFQESH 612
                     |.::.:::|..|:| :..|||:|:|:|.:...|...::|||| .:.:........|
  Fly   324 LDLFSSGATLGVARLLIHEQYNPNVYTDADLALLQLSNHVDIGDYIKPICL-WNENFLLELPSGH 387

Human   613 IT-VAGWNVLADVRSPGFKNDTLRSGVVSVVDSL--------LCEEQHEDHGIPVSVTDNMFCAS 668
            .: ||||.  .|.:.    |...|...::..|.:        |.||..:      .:|.:..|||
  Fly   388 KSYVAGWG--EDEKG----NRNTRLAKMTDTDIITQWECRGNLSEENAK------FITSHTICAS 440

Human   669 WEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKT--CSHRLSTAFTKVLPFKDW 731
              ....|..|:.::||...:      ..:..|.|.|:||.....|  |:..|...:|.|....:|
  Fly   441 --NAQASGPCSGDSGGGLML------QEQDIWMLRGVVSAGQRMTNRCNLTLPVIYTDVAKHIEW 497

Human   732 IERNM 736
            :..:|
  Fly   498 LLSSM 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAMR1	NP_056245.2	CUB	128..234	CDD:238001
		EGF_CA	240..272	CDD:238011
		CCP	297..360	CDD:153056	13/80 (16%)
		CCP	<425..460	CDD:153056	6/34 (18%)
		Tryp_SPc	478..735	CDD:238113	68/286 (24%)
CG9649	NP_650343.1	GD_N	29..132	CDD:464985	18/69 (26%)
		Tryp_SPc	257..498	CDD:238113	67/293 (23%)