Protein Alignment GALNT1 and Pgant9

DIOPT Version :9

• Sequence 1: NP_001371367.1
• Gene: GALNT1 / 2589
• HGNCID: 4123
• Length: 559
• Species: Homo sapiens
• Sequence 2: NP_001097342.1
• Gene: Pgant9 / 246627
• FlyBaseID: FBgn0050463
• Length: 650
• Species: Drosophila melanogaster
• Alignment Length: 530
• Identity: 264/530 - (49%)
• Similarity: 339/530 - (63%)
• Gaps: 28/530 - (5%)

Human    35 DEKKERGLPAGDVLEPVQKPHEGPGEMGKPVVIPKEDQEKMKEM----FKINQFNLMASEMIALN 95
            |.||        |::|.....|.|||:||||.:|||..::||:.    :..|.||...|::|:::
  Fly   131 DSKK--------VIDPPANFEENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSDLISVH 187

Human    96 RSLPDVRLEGCKTKV-YPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASE 159
            |:|||.|...||.:. |..|||.|.|:|.||||||:.||||||||::|||.|:|.:|:||||.|:
  Fly   188 RTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSD 252

Human   160 RDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLA 224
            ...|||.||.|..... .|.:||.::|.||||||:.||..:|..|:|:||:|||||.|||||||.
  Fly   253 MPHLKRQLEDYFAAYP-KVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGWLEPLLD 316

Human   225 RIKHDRRTVVCPIIDVISDDTFE--YMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVR 287
            ||..:..|||||:||||||:|.|  |.....:..|||:|.|.|.|:|||:||. :|......||.
  Fly   317 RIARNSTTVVCPVIDVISDETLEYHYRDSGGVNVGGFDWNLQFSWHPVPERER-KRHNSTAEPVY 380

Human   288 TPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPY 352
            :||||||||||||::|..:||||:|.|||||||||:||:.|.||||||||.||||||:|||.:||
  Fly   381 SPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPY 445

Human   353 TFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLEN 417
            .:..|. .::.||:.|||||||||:..::| ...|..|.|:||:|.|..||:.|:||.|.|||:|
  Fly   446 KWRSGV-NVLKKNSVRLAEVWMDEYSQYYY-HRIGNDKGDWGDVSDRRKLRNDLKCKSFKWYLDN 508

Human   418 IYPDSQIPRHYFSLGEIRNV--ETNQCLDNMARKENEK--VGIFNCHGMGGNQVFSYTANKEIRT 478
            |||:..||....:.|||||:  ....|||..|.|:::|  ||.:.||..||||.:..:...|||.
  Fly   509 IYPELFIPGDSVAHGEIRNLGYGGRTCLDAPAGKKHQKKAVGTYPCHRQGGNQYWMLSKAGEIRR 573

Human   479 DDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCNGS 543
            ||.|||.:  ...||:..||..||||.|.|......|.|..|.:||  |..|......:.:|:.|
  Fly   574 DDSCLDYA--GKDVTLFGCHGGKGNQFWTYRENTKQLHHGTSGKCL--AISESKDKLLMEECSAS 634

Human   544 RS-QQWLLRN 552
            .| |||.|.|
  Fly   635 LSRQQWTLEN 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GALNT1	NP_001371367.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..65		8/19 (42%)
		Catalytic subdomain A	115..225		65/109 (60%)
		pp-GalNAc-T	119..419	CDD:133004	172/301 (57%)
		Catalytic subdomain B	285..347		46/61 (75%)
		Ricin_B_lectin	432..548	CDD:395527	48/120 (40%)
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	159/274 (58%)
		pp-GalNAc-T	213..510	CDD:133004	172/300 (57%)
		Ricin_B_lectin	521..640	CDD:279046	48/122 (39%)
		RICIN	523..642	CDD:238092	50/122 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52215
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102903
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.730