| Sequence 1: | NP_001006657.1 | Gene: | ZNF473 / 25888 | HGNCID: | 23239 | Length: | 871 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_650051.1 | Gene: | CG6689 / 41345 | FlyBaseID: | FBgn0037877 | Length: | 613 | Species: | Drosophila melanogaster |
| Alignment Length: | 691 | Identity: | 158/691 - (22%) |
|---|---|---|---|
| Similarity: | 242/691 - (35%) | Gaps: | 187/691 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Human 233 REKPTVHQECEQGFDRNASLSVYPKTHTGYKFYV--CNEYGTTFSQSTYLWHQKTHTGEKPC--- 292
Human 293 -KSQDSDHPPSHDTQPGEHQKTHTDSKSYNC----NECGKAFTRIFHLTRHQKIHTRKRYECSKC 352
Human 353 QATFNLRKHLIQHQKTHAAKTTSECQECGKIFRHSSLLIEHQALHAGEEP----YKC----NERG 409
Human 410 KSFR-------HNSTLKIHQRVHSG----EKP----YKCSECGKAFHRHTHLNEHRRIHTGYRPH 459
Human 460 KCQECVRSFSRPSHLMRHQAIHTAEKPYSCAECKETFSDNNRLVQHQKMHTVKTPYECQECGERF 524
Human 525 ICGSTL-----------KCHESVHAREKQGFFVSGKI----LDQ-----------------NPEQ 557
Human 558 KEKCFKCNKCEKTFSCSKYLTQHERIHTR----GVKP--FECDQCGKAFGQSTRLIHHQRIHSRV 616
Human 617 RLYKWGEQGKAISSASLIKLQSFHTKEHPFKCNECGKTFSHSAHLSKH-QLIHAGENPFKCSKCD 680
Human 681 RVFTQRNYLVQHE-RTHARKKPLVCNECGKTFRQSSCLSKHQRIHSGEKP-------YVCDYCGK 737
Human 738 AFGLSAELVRHQRIHTGEKPYVCQECGKAFTQSSCLSIHRRVHTGEKPYRCGECGKAFAQKANLT 802
Human 803 QHQRIHTGEKPYSCNVCGKAFVLSAHLNQHLRVHTQETLYQ 843 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ZNF473 | NP_001006657.1 | KRAB_A-box | 6..45 | CDD:143639 | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 47..81 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 140..164 | ||||
| COG5048 | 207..614 | CDD:227381 | 96/451 (21%) | ||
| C2H2 Zn finger | 211..231 | CDD:275368 | |||
| C2H2 Zn finger | 239..259 | CDD:275368 | 6/19 (32%) | ||
| C2H2 Zn finger | 267..286 | CDD:275368 | 5/18 (28%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 290..318 | 7/31 (23%) | |||
| Interaction with SLBP/pre-mRNA complex | 312..552 | 50/281 (18%) | |||
| C2H2 Zn finger | 322..342 | CDD:275368 | 3/23 (13%) | ||
| C2H2 Zn finger | 349..369 | CDD:275368 | 3/19 (16%) | ||
| C2H2 Zn finger | 377..397 | CDD:275368 | 2/19 (11%) | ||
| C2H2 Zn finger | 405..425 | CDD:275368 | 8/30 (27%) | ||
| C2H2 Zn finger | 433..453 | CDD:275368 | 4/19 (21%) | ||
| COG5048 | 457..860 | CDD:227381 | 104/434 (24%) | ||
| C2H2 Zn finger | 461..481 | CDD:275368 | 4/19 (21%) | ||
| C2H2 Zn finger | 489..509 | CDD:275368 | 4/19 (21%) | ||
| C2H2 Zn finger | 517..537 | CDD:275368 | 3/30 (10%) | ||
| C2H2 Zn finger | 564..584 | CDD:275368 | 4/19 (21%) | ||
| C2H2 Zn finger | 593..613 | CDD:275368 | 10/19 (53%) | ||
| C2H2 Zn finger | 648..668 | CDD:275368 | 7/20 (35%) | ||
| C2H2 Zn finger | 676..696 | CDD:275368 | 5/20 (25%) | ||
| C2H2 Zn finger | 704..724 | CDD:275368 | 1/19 (5%) | ||
| C2H2 Zn finger | 732..752 | CDD:275368 | 5/19 (26%) | ||
| C2H2 Zn finger | 760..780 | CDD:275368 | 6/19 (32%) | ||
| C2H2 Zn finger | 788..808 | CDD:275368 | 7/19 (37%) | ||
| C2H2 Zn finger | 816..836 | CDD:275368 | 4/19 (21%) | ||
| C2H2 Zn finger | 844..864 | CDD:275368 | 158/691 (23%) | ||
| CG6689 | NP_650051.1 | THAP | 2..96 | CDD:283206 | 22/98 (22%) |
| zf-AD | 167..240 | CDD:214871 | 19/91 (21%) | ||
| zf-C2H2 | 385..407 | CDD:278523 | 13/48 (27%) | ||
| C2H2 Zn finger | 387..407 | CDD:275368 | 12/46 (26%) | ||
| zf-H2C2_2 | 399..422 | CDD:290200 | 9/45 (20%) | ||
| C2H2 Zn finger | 415..436 | CDD:275368 | 7/20 (35%) | ||
| C2H2 Zn finger | 444..460 | CDD:275368 | 3/15 (20%) | ||
| C2H2 Zn finger | 492..512 | CDD:275368 | 5/19 (26%) | ||
| C2H2 Zn finger | 520..540 | CDD:275368 | 6/19 (32%) | ||
| C2H2 Zn finger | 547..567 | CDD:275368 | 7/19 (37%) | ||
| zf-met | 574..597 | CDD:289631 | 5/26 (19%) | ||
| C2H2 Zn finger | 575..591 | CDD:275368 | 4/19 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24376 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 2.010 | |||||