Protein Alignment GALR1 and AstA-R2

DIOPT Version :9

• Sequence 1: NP_001471.2
• Gene: GALR1 / 2587
• HGNCID: 4132
• Length: 349
• Species: Homo sapiens
• Sequence 2: NP_001263042.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Alignment Length: 317
• Identity: 115/317 - (36%)
• Similarity: 172/317 - (54%)
• Gaps: 22/317 - (6%)

Human    40 FGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLG 104
            ||:|...|..||.|||.|:..:  ...||||||.|:||:.|||.:::.||||.||.|.:..|..|
  Fly    45 FGVIAITGFFGNLLVILVVVFN--NNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYWPYG 107

Human   105 AFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASP 169
            .|.|:.:.|...|:...||:||..||:||::|:||..||..:|.....|:.:..:|.:.:.::.|
  Fly   108 RFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVVSVP 172

Human   170 VAY-HQGLFHPRASNQ------TFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHL 227
            ||: |..:....|...      ||....:..||   .|.|..|:..|||||::|...|.:::..|
  Fly   173 VAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPR---TYQVTFFISSYLLPLMIISGLYMRMIMRL 234

Human   228 HKKLK--NMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPL-TPASFLFRITAH 289
            .::..  .|||:|:..:|:..:.|:|||:.|...|||..:|.|.....|... |....:.::||.
  Fly   235 WRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETNTLTKLVIQVTAQ 299

Human   290 CLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNC 346
            .||||:|.:||::|||||||||||:.:...|..|..::.||       :..|..|:|
  Fly   300 TLAYSSSCINPLLYAFLSENFRKAFYKAVNCSSRYQNYTSD-------LPPPRKTSC 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GALR1	NP_001471.2	7tm_1	50..303	CDD:278431	93/262 (35%)
AstA-R2	NP_001263042.1	7tm_4	47..>164	CDD:304433	48/118 (41%)
		7tm_1	55..313	CDD:278431	93/262 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	176	1.000	Domainoid score	I3617
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3667
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1294084at2759
OrthoFinder	1	1.000	-	-		FOG0000972
OrthoInspector	1	1.000	-	-		mtm9822
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.970