Protein Alignment WHRN and mics-1

DIOPT Version :9

• Sequence 1: XP_011516787.1
• Gene: WHRN / 25861
• HGNCID: 16361
• Length: 918
• Species: Homo sapiens
• Sequence 2: NP_001343863.1
• Gene: mics-1 / 179475
• WormBaseID: WBGene00011890
• Length: 293
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 75/324 - (23%)
• Similarity: 119/324 - (36%)
• Gaps: 97/324 - (29%)

Human   101 SDQLLFDQYTAEGLYLPATTPYRQPAWGGPDSAGPGEVRLVSLRRAKAHEGLGFSIRGGSEH--- 162
            :|.:.|:..|.:|              .|.:|.....:.:|.:.  |..:|.||:|.||:::
 Worm    48 TDDMTFNDTTTDG--------------NGQESVPLEALTVVEIE--KTSKGFGFNIVGGTDNPHF 96

Human   163 --GVGIYVSLVEPGSLAEKEG-LRVGDQILRVNDKSLARVTHAEAVKALKG------SKKLVLSV 218
              .:|||||.|  .|.::..| :|.||:||..:...:...||.|||:..:.      :|.|:...
 Worm    97 VGDIGIYVSSV--NSESKSYGVVRTGDKILSFDGIDMTYKTHDEAVEVFRSVKIGHVAKMLIDRE 159

Human   219 Y-----SAGRIPGGYVTNHIYTWVDPQGRSISPPSGLPQPHGGALRQQEGDRRSTLHLLQGGDEK 278
            |     ...:.|...|:  |...|.||.||....:..|:    ::...|...|.|.|.|....|:
 Worm   160 YLHLQEDRTQTPTASVS--ITPQVTPQTRSTQNNTDTPK----SMSHSESKSRLTSHGLSAVIER 218

Human   279 KVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSGLKVGDQILEVNGRSFLNILHDEAV 343
                           |||      .:|        |.|.:                      ::|
 Worm   219 ---------------IRG------KVY--------EEEDA----------------------QSV 232

Human   344 RLLKSSRHLILTVKDVGRLPHARTTVDETKWIASSRIRETMANSAGFLGDLTTEGINKPGFYKG 407
            .....|.|.|  :.||.|.|....::.:.:  .:|.:.|.:..|.| ||.||..|.....|.:|
 Worm   233 TSYAPSTHSI--IDDVPRTPRKPLSLLDPR--NNSWLTEALYVSIG-LGALTISGYLAYRFIRG 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WHRN	XP_011516787.1	HN_L-whirlin_R1_like	37..112	CDD:259822	3/10 (30%)
		PDZ_signaling	138..215	CDD:238492	27/88 (31%)
		PDZ_signaling	277..357	CDD:238492	11/79 (14%)
		HN_L-whirlin_R2_like	419..499	CDD:259823
		PDZ_signaling	827..898	CDD:238492
mics-1	NP_001343863.1	PDZ_signaling	71..145	CDD:238492	26/77 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810