Protein Alignment POU2F3 and acj6

DIOPT Version :10

• Sequence 1: NP_001231611.1
• Gene: POU2F3 / 25833
• HGNCID: 19864
• Length: 438
• Species: Homo sapiens
• Sequence 2: NP_524876.1
• Gene: acj6 / 47080
• FlyBaseID: FBgn0000028
• Length: 396
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 132/361 - (36%)
• Similarity: 175/361 - (48%)
• Gaps: 72/361 - (19%)

Human    44 NRQIKTEDLSDSLQQTLSHRPCHL-SQGPAMMSGNQMSGLN---ASPCQDMASL----HPLQQLV 100
            |..|......|||:..|......| :...|..:|:..:|:|   .|..:.:|::    |..|.:
  Fly    40 NPSIHISSSCDSLESRLLEDASLLCNSWSARQNGDIFAGINDGILSRAEALAAVDIQKHQAQHV- 103

Human   101 LVPGHLQSVSQFL-------LSQTQPGQQGLQPNLLPFPQQ------QSGLLLPQTG--PGLA-- 148
                |.|..||..       .|.:.|.|:.||.|  ||.:|      |..:|.| ||  ..||
  Fly   104 ----HSQMPSQIKHDVMYHHHSMSGPPQRPLQEN--PFSRQMHHSMDQLDMLDP-TGSMTTLAPI 161

Human   149 ---------------------SQAFGHPG-LPGSSLEPHLEASQHLPVPKHLPSSGG--ADEPSD 189
                                 ..:..||| |.|.:...|..::.|.||.....::.|  .|..:|
  Fly   162 SESPLTPTHQHLHGSYHSMNHMMSHHHPGTLSGHTGGHHGHSAVHHPVITAAVAAAGLHPDTDTD 226

Human   190 LEELEKFAKTFKQRRIKLGFTQGDVGLAMG--KLYG-NDFSQTTISRFEALNLSFKNMCKLKPLL 251
            ..|||.||:.|||||||||.||.|||.|:.  ||.| ...||:||.|||:|.||..||..|||:|
  Fly   227 PRELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPIL 291

Human   252 EKWLNDAESSPS----DPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEE 312
            :.||.:||:...    ||  ..||..|:     |.|::|||||....:.:||..|...|:||.|:
  Fly   292 QAWLEEAEAQAKNKRRDP--DAPSVLPA-----GEKKRKRTSIAAPEKRSLEAYFAVQPRPSGEK 349

Human   313 ISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATP 348
            |:.|||:|.::|.||||||||:|||:|||...| ||
  Fly   350 IAAIAEKLDLKKNVVRVWFCNQRQKQKRIVSSV-TP 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POU2F3	NP_001231611.1	POU	185..259	CDD:197673	43/76 (57%)
		Homeodomain	284..340	CDD:459649	29/55 (53%)
acj6	NP_524876.1	POU	222..299	CDD:197673	43/76 (57%)
		Homeodomain	321..377	CDD:459649	29/55 (53%)