Protein Alignment POU2F3 and pdm3

DIOPT Version :10

• Sequence 1: NP_001231611.1
• Gene: POU2F3 / 25833
• HGNCID: 19864
• Length: 438
• Species: Homo sapiens
• Sequence 2: NP_001188885.2
• Gene: pdm3 / 35813
• FlyBaseID: FBgn0261588
• Length: 1292
• Species: Drosophila melanogaster
• Alignment Length: 450
• Identity: 113/450 - (25%)
• Similarity: 167/450 - (37%)
• Gaps: 139/450 - (30%)

Human     3 SPRTAKGGRDIKMSGDVADSTDARSTLSQVEPGNDRNGLD-FNRQIKTEDLSDSLQQTLSHRPCH 66
            ||:.:..||    .|....||.....|||....:||  |: ..||.:.|..|.:...|.:.....
  Fly   858 SPKHSPQGR----MGGSGGSTTTGMNLSQHHERHDR--LERLERQERHERRSHTPTATATRASVS 916

Human    67 LSQGPAMMSGNQMSGLNASP-----------CQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPG 120
            .|.......|:..||..:.|           ..|.....||.:.....||..|:.         |
  Fly   917 SSSSAGHHGGSLPSGRLSPPSSAPSNSAANSISDRGYTSPLFRTHSPQGHALSLG---------G 972

Human   121 QQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLE---------------------- 163
            ...|:.:.|     .:|   |.:|...::.:.|.|...|||..
  Fly   973 SPRLERDYL-----GNG---PSSGTATSTSSCGAPTAAGSSATANVLSSINRLNASNGELTITKS 1029

Human   164 ------------------------PHLEASQHL-PV---------PKHLPSSG----------GA 184
                                    |...:..|: |:         |.||..:|          ..
  Fly  1030 LGAPTATATRASSASPRDDSPGPGPSTSSVSHMQPLKLSPSSRSEPPHLSPNGNDNDNDLLMDSP 1094

Human   185 DEPS------------DLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTI------ 231
            :||:            ||:|:::|||.||.||:.||.||..||.|:....|..:||:.|
  Fly  1095 NEPTINQATTNVVDGIDLDEIKEFAKAFKLRRLSLGLTQTQVGQALSVTEGPAYSQSAICSSALA 1159

Human   232 -------------SRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFG-- 281
                         :.||.|:::.|:..|:||:||:|:.:||.|..:   ...|....|::..|
  Fly  1160 AQMYAAQLSTQQQNMFEKLDITPKSAQKIKPVLERWMKEAEESHWN---RYKSGQNHLTDYIGVE 1221

Human   282 --RKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEK 339
              :|||:|||........|...|:.|..||..||:.:|.||..|:||:|:||||:||..|
  Fly  1222 PSKKRKRRTSFTPQALELLNAHFERNTHPSGTEITGLAHQLGYEREVIRIWFCNKRQALK 1281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POU2F3	NP_001231611.1	POU	185..259	CDD:197673	33/104 (32%)
		Homeodomain	284..340	CDD:459649	25/55 (45%)
pdm3	NP_001188885.2	Pou	1108..1200	CDD:473999	31/91 (34%)
		Homeodomain	1226..1282	CDD:459649	25/55 (45%)