Protein Alignment TMEM184B and CG5850

DIOPT Version :10

• Sequence 1: XP_016884243.1
• Gene: TMEM184B / 25829
• HGNCID: 1310
• Length: 452
• Species: Homo sapiens
• Sequence 2: NP_001260310.1
• Gene: CG5850 / 34327
• FlyBaseID: FBgn0032172
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 380
• Identity: 113/380 - (29%)
• Similarity: 191/380 - (50%)
• Gaps: 55/380 - (14%)

Human    82 ISGFFVWTALLITCHQIYMHLRCYSCPNEQRYIVRILFIVPIYAFDSWLSLLFFTNDQYYVYFGT 146
            |.|.||.:|:.::...|..|:..::.|..|::|:|||::|||||.::|:.|.|   .::.:|..:
  Fly    54 IGGLFVLSAVPVSIWHIIQHVIHFTKPILQKHIIRILWMVPIYALNAWIGLFF---PKHSIYVDS 115

Human   147 VRDCYEALVIYNFLSLCYEYLGGESSIMSEIRGKPIESSCMYGTCCLWGKTYSIG--FLRFCKQA 209
            :|:||||.|||||:.....||.....:.:.:..|| :....:..||:  :.:.:|  |:..||..
  Fly   116 LRECYEAYVIYNFMVYLLNYLNLGMDLEATMEYKP-QVPHFFPLCCM--RPWVMGREFIHNCKHG 177

Human   210 TLQFCVVKPLMAVSTVVLQAFGKYRDGDFDVTSGYLYVTIIYNISVSLALYALFLFYFATRELLS 274
            .||:.||:|:....:|:.:..|.|.:|:|.....:.|:.::.|||..:|:|.|.|||.|.:|.|.
  Fly   178 ILQYTVVRPITTFISVICELCGVYGEGEFAGNVAFPYIVVVNNISQFVAMYCLVLFYRANKEDLK 242

Human   275 PYSPVLKFFMVKSVIFLSFWQGMLLAILEKCGAIPKIHSARVSVGEGTVAAGYQDFIICVEMFFA 339
            |..|:.||..:|:|:|.||:||:||.:|.....|..|..:  .||:..:|:..|:|:||:|||.|
  Fly   243 PMKPIPKFLCIKAVVFFSFFQGVLLNVLVYYNIIKDIFGS--DVGDTNLASLLQNFLICIEMFIA 305

Human   340 ALALRHAFTYKVYADKRLDAQASSPAPPAPCPAGRCAPMKSISSSLKETMNPHDIVQDAIHNFSP 404
            |:|..::|.:..:       ..:||                     :...||:       |::..
  Fly   306 AVAHIYSFPHHPF-------HINSP---------------------QYWNNPN-------HSWCR 335

Human   405 AYQQYTQQSTLEPGPTWRGGAHGLSRSHSLSG-------ARDNEKTLLLSSDDEF 452
            |:......|.::...|...|..|.|.|....|       ||...::   ||:.|:
  Fly   336 AFLSMMDISDMQEDVTEHLGVVGSSLSRRFQGRSTYQPLARSPRRS---SSESEY 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM184B	XP_016884243.1	Solute_trans_a	79..352	CDD:460991	95/271 (35%)
CG5850	NP_001260310.1	Solute_trans_a	51..318	CDD:460991	95/271 (35%)