DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DNAJB5 and Csp

DIOPT Version :9

Sequence 1:	NP_001128477.1	Gene:	DNAJB5 / 25822	HGNCID:	14887	Length:	420	Species:	Homo sapiens
Sequence 2:	NP_001287144.1	Gene:	Csp / 40459	FlyBaseID:	FBgn0004179	Length:	249	Species:	Drosophila melanogaster

Alignment Length:	231	Identity:	63/231 - (27%)
Similarity:	82/231 - (35%)	Gaps:	94/231 - (40%)

- Green bases have known domain annotations that are detailed below.

Human    70 VAVMGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKE-PNAEEKFKEIAEAYDVLSDPKKR 133
            ::..|...|:|||:|..|..|:|||.|||:|||||||||.: .:|.:||||:..|:.:|||..||
  Fly    11 LSTSGDSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKR 75

Human   134 GLYDQYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRS--------- 189
            .:||.||..||                        ..|..||..|....|..:|.:
  Fly    76 NIYDNYGSLGL------------------------YIAEQFGEENVNAYFVVTSPAVKAVVICCA 116

Human   190 ------------------------------------TRPFSGFDPDDM-----------DVDEDE 207
                                                .||....:.:||           |||.|:
  Fly   117 VITGCCCCCCCCCCCNFCCGKFKPPVNESHDQYSHLNRPDGNREGNDMPTHLGQPPRLEDVDLDD 181

Human   208 DPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPV 243
            ...||.|             ||....||.:....||
  Fly   182 VNLGAGG-------------APVTSQPREQAGGQPV 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB5	NP_001128477.1	DnaJ	72..415	CDD:223560	63/229 (28%)
Csp	NP_001287144.1	DnaJ	17..>86	CDD:223560	37/68 (54%)
Csp	NP_001287144.1	DnaJ	17..79	CDD:278647	33/61 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910