Protein Alignment DNAJB5 and DnaJ-1

DIOPT Version :9

• Sequence 1: NP_001128477.1
• Gene: DNAJB5 / 25822
• HGNCID: 14887
• Length: 420
• Species: Homo sapiens
• Sequence 2: NP_523936.2
• Gene: DnaJ-1 / 38643
• FlyBaseID: FBgn0263106
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 183/361 - (50%)
• Similarity: 237/361 - (65%)
• Gaps: 43/361 - (11%)

Human    73 MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRGLYD 137
            ||||:|||||:...|::|||||||||:||||||||||.|.|||:||||||||:||||.|||.::|
  Fly     1 MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFD 65

Human   138 QYGEEGLKTG--GGTSGGSSGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSTRPFSG----- 195
            .|||:|||.|  |...||..|::.|.|||||.||||.|||.|:||..||....:.  |||
  Fly    66 NYGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNM--FSGGQGGN 128

Human   196 -------FDPDDMDVDEDEDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEE 253
                   ...|||              |.||.      :||.    |::.||||:.|:|.|||||
  Fly   129 TNEIFWNIGGDDM--------------FAFNA------QAPS----RKRQQDPPIEHDLFVSLEE 169

Human   254 IYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVL 318
            :..|..|:|||:|.....:|  ...|:|:|.|.:|.|||.|||||||:|||:.|:..||||||::
  Fly   170 VDKGCIKKMKISRMATGSNG--PYKEEKVLRITVKPGWKAGTKITFPQEGDSAPNKTPADIVFII 232

Human   319 KDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDG-RVIPLPCNDVIKPGTVKRLRGEGLP 382
            :||||:.|:|:|.::.|:|.||||:||||..|::||:.| |:...|.:::|||.|.:|:.|.|||
  Fly   233 RDKPHSLFKREGIDLKYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLP 297

Human   383 FPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLP 418
            .||.|::||||||.|.::|||.|.|..:..|.:.||
  Fly   298 VPKEPSRRGDLIVSFDIKFPDTLAPSLQNQLSELLP 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB5	NP_001128477.1	DnaJ	72..415	CDD:223560	181/356 (51%)
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	181/359 (50%)
		DnaJ	4..65	CDD:278647	45/60 (75%)
		DnaJ_C	157..320	CDD:199909	86/164 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154096
Domainoid	1	1.000	190	1.000	Domainoid score	I3265
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2129
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	1	1.010	-	-		D1393097at2759
OrthoFinder	1	1.000	-	-		FOG0000274
OrthoInspector	1	1.000	-	-		mtm8440
orthoMCL	1	0.900	-	-		OOG6_100302
Panther	1	1.100	-	-	O	PTHR24078
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770