Protein Alignment KLK5 and CG17234

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_722785.1
• Gene: CG17234 / 59225
• FlyBaseID: FBgn0042187
• Length: 251
• Species: Drosophila melanogaster
• Alignment Length: 237
• Identity: 71/237 - (29%)
• Similarity: 110/237 - (46%)
• Gaps: 28/237 - (11%)

Human    66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC---------RKKVFRVRLGHY 121
            |||.|....:...|||.:|....:.: ||..:.....::|||||         ..:.::||.|
  Fly    26 RIIGGEPIGIEQVPWQVSLQYFGDHV-CGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAG-- 87

Human   122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL 186
              |.:.:|...:......|.|..|:...:.||:.:::|:..:..|..|:||.::...|...:..|
  Fly    88 --SALTDSNGTLVDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPIPLAKTNPYPRSIAL 150

Human   187 VSGWGTT----KSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGG 247
            |||||.:    .|..: :|..||.|.:.:.|...|     |..|.::.||| ..||.:|.|||||
  Fly   151 VSGWGVSYILNDSTNL-YPTHLQGLALHIKSIFSC-----RLFDPSLLCAG-TYGRTACHGDSGG 208

Human   248 PVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289
            |:|.|..|.|:||||...|.   ....:.::..|.:||...|
  Fly   209 PLVVNKQLVGVVSWGRKGCV---SSAFFVSVPYFREWILNAI 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/1 (100%)
		Tryp_SPc	66..285	CDD:214473	68/231 (29%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	67/230 (29%)