Protein Alignment KLK5 and CG18735

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Alignment Length: 246
• Identity: 90/246 - (36%)
• Similarity: 128/246 - (52%)
• Gaps: 38/246 - (15%)

Human    66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGHYSLSPV 126
            ||:.|.:.::|..||...|:...| .||||.||:.|:.||||||    ..::..|||..::....
  Fly    82 RIVGGQETEVHEYPWMIMLMWFGN-FYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDS 145

Human   127 YESGQQMFQGVKSIP--------HPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS--- 180
            :         ||.:.        ||.||.....:|:.||:.|..:|...|:.|:.:.:  ||
  Fly   146 H---------VKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPT--PSENY 199

Human   181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAY--PRQIDDTMFCAG--DKAGRDSC 241
            ||...:|:|||.. |........||.:.:.:|||:.|.::.  ..:|.|.|.|||  ::.|:|||
  Fly   200 AGQTAVVTGWGAL-SEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSC 263

Human   242 QGDSGGPVVCNGS-----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
            |||||||:...||     |.|:||||: .||:||.|||||.:..|..||.|
  Fly   264 QGDSGGPMHVLGSGDAYQLAGIVSWGE-GCAKPNAPGVYTRVGSFNDWIAE 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/1 (100%)
		Tryp_SPc	66..285	CDD:214473	87/242 (36%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	89/245 (36%)