Protein Alignment KLK5 and CG34436

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001097954.1
• Gene: CG34436 / 5740743
• FlyBaseID: FBgn0085465
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 307
• Identity: 74/307 - (24%)
• Similarity: 117/307 - (38%)
• Gaps: 88/307 - (28%)

Human    18 ALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDAR-SDDSSSRIINGSDCDMHTQPWQ 81
            |..|.|...:|||             .||.|.|.....|.:| |:|.           :.::||.
  Fly     4 ASCLAVLSWMLAN-------------QGSAQLLDQNCAEVSRLSNDI-----------IFSRPWM 44

Human    82 AALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFR-----VRLGHYSLSP----VYESGQQMFQGV 137
            |.:|| ||:. |...|:|..:::|:|.|   ||.     ||||..|:..    .|.|.....|
  Fly    45 ALVLL-PNKT-CSGALIHKYFVITSASC---VFNQERAIVRLGQLSIKQEHIVSYSSDDYHVQ-- 102

Human   138 KSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL---------------- 186
            .:..|..|......:|:.|::|...:.....:|||            ||
  Fly   103 SAYIHRFYEKSNFEHDIALLELQNDVLYKAHIRPI------------CLWLDKSDIDTQMFKRYE 155

Human   187 VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVV- 250
            ...||..:.   :.....:...|..:||.:||:|:.....::..|||.| .:..|. ::|.|:.
  Fly   156 TFRWGIDEK---YILPAAKTSKIKHISQVKCENAFKLYPQNSHICAGYK-NKSKCV-ETGSPLFK 215

Human   251 -------CNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
                   ...:|.|:.|:|:      :|..:||::.|:..||...||
  Fly   216 KIRYYTKIRYTLFGIQSYGE------SRTCLYTDVTKYIDWIMGVIQ 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		8/31 (26%)
		Tryp_SPc	66..285	CDD:214473	56/251 (22%)
CG34436	NP_001097954.1	Tryp_SPc	40..252	CDD:473915	57/241 (24%)