Protein Alignment KLK5 and deltaTry

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_523694.2
• Gene: deltaTry / 48343
• FlyBaseID: FBgn0010358
• Length: 253
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 87/252 - (34%)
• Similarity: 124/252 - (49%)
• Gaps: 27/252 - (10%)

Human    41 TVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLT 105
            |||.|....|             ..||:.||...:.:.|||.: |.|.....||..:.....::|
  Fly    18 TVPEGLLPQL-------------DGRIVGGSATTISSFPWQIS-LQRSGSHSCGGSIYSSNVIVT 68

Human   106 AAHCRK----KVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPT 166
            ||||.:    .|.::|.|    |..:.||...|.......|.||:.....||:.:||:|..:..:
  Fly    69 AAHCLQSVSASVLQIRAG----SSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFS 129

Human   167 KDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDA---YPRQIDDT 228
            ..::.|.::|..|:.|....||||||........|..||.:|::::||.:|..:   |..||..|
  Fly   130 STIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRST 194

Human   229 MFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            |.||. .:|:|:||||||||:|..|.|.|:|||| |.||..|.||||.::.....|:
  Fly   195 MICAA-ASGKDACQGDSGGPLVSGGVLVGVVSWG-YGCAYSNYPGVYADVAALRSWV 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/26 (23%)
		Tryp_SPc	66..285	CDD:214473	81/225 (36%)
deltaTry	NP_523694.2	Tryp_SPc	30..249	CDD:214473	81/225 (36%)