Protein Alignment KLK5 and alphaTry

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 290
• Identity: 94/290 - (32%)
• Similarity: 138/290 - (47%)
• Gaps: 52/290 - (17%)

Human    11 VLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDM 75
            |:|||                       ..|||.|....|             ..||:.||...:
  Fly    11 VVCAL-----------------------GGTVPEGLLPQL-------------DGRIVGGSATTI 39

Human    76 HTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRK----KVFRVRLGHYSLSPVYESGQQMFQG 136
            .:.|||.: |.|.....||..:.....::|||||.:    .|.:||.|    |..:.||..:.:.
  Fly    40 SSFPWQIS-LQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAG----STYWSSGGVVAKV 99

Human   137 VKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFP 201
            .....|.||:.....||:.:|:|:..:..:..::.|:::::.|:.|....||||||..|.....|
  Fly   100 SSFKNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAISLATYNPANGASAAVSGWGTQSSGSSSIP 164

Human   202 KVLQCLNISVLSQKRCEDA---YPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGD 263
            ..||.:|::::||.:|..:   |..||.:||.||. .:|:|:||||||||:|..|.|.|:||||
  Fly   165 SQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAA-ASGKDACQGDSGGPLVSGGVLVGVVSWG- 227

Human   264 YPCARPNRPGVYTNLCKFTKWIQETIQANS 293
            |.||..|.||||.::.....|:..|  |||
  Fly   228 YGCAYSNYPGVYADVAVLRSWVVST--ANS 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/30 (20%)
		Tryp_SPc	66..285	CDD:214473	80/225 (36%)
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	80/225 (36%)