Protein Alignment KLK5 and betaTry

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_524904.1
• Gene: betaTry / 47901
• FlyBaseID: FBgn0010357
• Length: 253
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 83/252 - (32%)
• Similarity: 126/252 - (50%)
• Gaps: 27/252 - (10%)

Human    41 TVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLT 105
            |:|.|....|             ..||:.|:...:.:.|||.: |.|.....||..:...:.::|
  Fly    18 TIPEGLLPQL-------------DGRIVGGTATTISSFPWQIS-LQRSGSHSCGGSIYSARVIVT 68

Human   106 AAHCRKKV----FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPT 166
            ||||.:.|    .::|.|    |..:.||..:.:......|.||:.....||:.::.|:..:..:
  Fly    69 AAHCLQSVSASSLQIRAG----SSYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVLHLSSSLSFS 129

Human   167 KDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDA---YPRQIDDT 228
            ..::.|.::|..|:.|....||||||..|.....|..|:.:|::::||.||..:   |..||..:
  Fly   130 STIKAIGLASSNPANGAAASVSGWGTESSGSSSIPSQLRYVNVNIVSQSRCSSSSYGYGNQIKSS 194

Human   229 MFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            |.|| ..:|:||||||||||:|..|.|.|:|||| |.||..|.||||.::.....|:
  Fly   195 MICA-FASGKDSCQGDSGGPLVSGGVLVGVVSWG-YGCAAANYPGVYADVAALRSWV 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		5/26 (19%)
		Tryp_SPc	66..285	CDD:214473	78/225 (35%)
betaTry	NP_524904.1	Tryp_SPc	30..249	CDD:214473	78/225 (35%)