Protein Alignment KLK5 and Jon99Ci

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_524555.1
• Gene: Jon99Ci / 43545
• FlyBaseID: FBgn0003358
• Length: 272
• Species: Drosophila melanogaster
• Alignment Length: 301
• Identity: 71/301 - (23%)
• Similarity: 115/301 - (38%)
• Gaps: 68/301 - (22%)

Human    15 LITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQP 79
            |::...|||...:...:  |..||         :||      :.|......||.||:.......|
  Fly     6 LLSLAFLGVCSALTVPH--SLVHP---------RDL------EIRHGGIEGRITNGNLASEGQVP 53

Human    80 WQAALLLRP--NQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPH 142
            :...:.|..  |..:||..::...|:||||||........|               :.|..:...
  Fly    54 YIVGVSLNSNGNWWWCGGSIIGHTWVLTAAHCTAGADEASL---------------YYGAVNYNE 103

Human   143 PGYSHP-------------GHSNDLMLIK---------LNRRIRPTKDVRPINVSSHCPSAGTKC 185
            |.:.|.             |..:||.|||         :|:...|:.|.|..:..::...|
  Fly   104 PAFRHTVSSENFIRYPHYVGLDHDLALIKTPHVDFYSLVNKIELPSLDDRYNSYENNWVQA---- 164

Human   186 LVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ-IDDTMFCAGDKAGRDSCQGDSGGPV 249
              :|||...... :..:.|:.:::.|:|...|:..|... ..:...|.....|:.:||||||||:
  Fly   165 --AGWGAIYDGS-NVVEDLRVVDLKVISVAECQAYYGTDTASENTICVETPDGKATCQGDSGGPL 226

Human   250 VC--NGSLQGLVSW-GDYPCARPNRPGVYTNLCKFTKWIQE 287
            |.  ...|.|:.|: ..|.| :...|..:|.:.|:.:||:|
  Fly   227 VTKEGDKLIGITSFVSAYGC-QVGGPAGFTRVTKYLEWIKE 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/30 (20%)
		Tryp_SPc	66..285	CDD:214473	58/246 (24%)
Jon99Ci	NP_524555.1	Tryp_SPc	41..266	CDD:238113	59/247 (24%)