Protein Alignment KLK5 and Jon99Ciii

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_733330.1
• Gene: Jon99Ciii / 43543
• FlyBaseID: FBgn0003357
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 71/247 - (28%)
• Similarity: 103/247 - (41%)
• Gaps: 39/247 - (15%)

Human    62 DSSSRIINGSDCDMHTQPWQAALLLRPN-QLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS- 124
            |...||.||........|:...||...| ..:||..::...|:||||||......|.: :|..|
  Fly    31 DIQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGGSIIGNTWVLTAAHCTNGASGVTI-NYGASI 94

Human   125 ---PVYE----SGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS-- 180
               |.|.    ||.       .|.|..|:.....||:.||:     .|..|...:......||
  Fly    95 RTQPQYTHWVGSGD-------IIQHHHYNSGNLHNDISLIR-----TPHVDFWSLVNKVELPSYN 147

Human   181 ------AGTKCLVSGWGTT--KSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAG 237
                  ||...:.||||.|  .||   .|..||.:::.::||..|...:  .:.|.|.|.....|
  Fly   148 DRYQDYAGWWAVASGWGGTYDGSP---LPDWLQSVDVQIISQSDCSRTW--SLHDNMICINTDGG 207

Human   238 RDSCQGDSGGPVVCN--GSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
            :.:|.||||||:|.:  ..|.|:.|:|.....:...|.|::.:..:..||::
  Fly   208 KSTCGGDSGGPLVTHDGNRLVGVTSFGSAAGCQSGAPAVFSRVTGYLDWIRD 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/5 (40%)
		Tryp_SPc	66..285	CDD:214473	68/239 (28%)
Jon99Ciii	NP_733330.1	Tryp_SPc	36..260	CDD:238113	69/242 (29%)