Protein Alignment KLK5 and CG7829

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_651732.1
• Gene: CG7829 / 43522
• FlyBaseID: FBgn0039703
• Length: 253
• Species: Drosophila melanogaster
• Alignment Length: 242
• Identity: 67/242 - (27%)
• Similarity: 117/242 - (48%)
• Gaps: 22/242 - (9%)

Human    57 DARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLY----CGAVLVHPQWLLTAAHCRK----KV 113
            ::|.|   .||:.|...|:...|:..::     |||    ||..:::...:|||.||..    ::
  Fly    21 ESRPD---PRIVGGFPADIANIPYIVSI-----QLYGIHHCGGSIINNHTILTAGHCLNGVPHRL 77

Human   114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHC 178
            .:|::|..|.   |....::|.......|..::......|:.:|:|.:.:..::.|:.|.::...
  Fly    78 LKVKVGGTSR---YRKDGELFSVADLQVHENFNPKTMDYDIGIIRLTKNLTLSRKVKAIPINPER 139

Human   179 PSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQ 242
            .:.||...::||| .||........|:...:.:::|..|.:...:.:.|.|.|||. |.|.|:||
  Fly   140 VAEGTYATIAGWG-FKSMNGPPSDSLRYARVPIVNQTACRNLLGKTVTDRMLCAGYLKGGTDACQ 203

Human   243 GDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289
            .|||||:.....|.|:|||| ..||..::||||:.|.....|:.:.:
  Fly   204 MDSGGPLSVREQLVGIVSWG-VGCALADKPGVYSRLDALHPWLDQVL 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		3/10 (30%)
		Tryp_SPc	66..285	CDD:214473	64/227 (28%)
CG7829	NP_651732.1	Tryp_SPc	27..244	CDD:214473	64/226 (28%)