Protein Alignment KLK5 and CG11843

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Alignment Length: 281
• Identity: 80/281 - (28%)
• Similarity: 116/281 - (41%)
• Gaps: 61/281 - (21%)

Human    53 GAGEDARSDDS----SSRIINGSDCDMHTQPWQAALLLRPN-----QLYCGAVLVHPQWLLTAAH 108
            ||..::|..|:    :..|:.|........|..|.|..||:     ..:||.||:..:::|||||
  Fly    50 GASIESRIIDNCRSYTPLIVGGHPAQPREFPHMARLGRRPDPSSRADWFCGGVLISERFVLTAAH 114

Human   109 C----RKKVFRVRLGHYSLSPVYESG---QQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRI--- 163
            |    |.:|..||||......:.|..   ..|..|.  |.||||..|...:|:.|:||...:
  Fly   115 CLESERGEVNVVRLGELDFDSLDEDAAPRDYMVAGY--IAHPGYEDPQFYHDIGLVKLTEAVVFD 177

Human   164 -------RPTKDVRPINVSSHCPSAGTKCLVSGWGTT---KSPQVHFPKV-LQ------CLNISV 211
                   .|.:|.|          :....:..|||:|   ..|.....|| ||      |..:..
  Fly   178 LYKHPACLPFQDER----------SSDSFIAVGWGSTGLALKPSAQLLKVKLQRYGNWVCKKLLT 232

Human   212 LSQKRCEDAYPRQID-DTMFCAGDKAGRDSCQGDSGGPVV-------CNGSLQGLVSWGDYPCAR 268
                |..:.:||..| :...|.|.:..:|:|.||||||::       |...:.|:.|.| ..|..
  Fly   233 ----RQVEEFPRGFDGNNQLCVGSEMAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAG-LSCGS 292

Human   269 PNRPGVYTNLCKFTKWIQETI 289
            |..||:||.:..:..||..|:
  Fly   293 PGIPGIYTRVYPYLGWIARTL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/18 (22%)
		Tryp_SPc	66..285	CDD:214473	73/258 (28%)
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	75/260 (29%)