DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment KLK5 and CG11842

DIOPT Version :10

Sequence 1:NP_036559.1 Gene:KLK5 / 25818 HGNCID:6366 Length:293 Species:Homo sapiens
Sequence 2:NP_651662.1 Gene:CG11842 / 43431 FlyBaseID:FBgn0039629 Length:319 Species:Drosophila melanogaster


Alignment Length:223 Identity:60/223 - (26%)
Similarity:94/223 - (42%) Gaps:27/223 - (12%)


- Green bases have known domain annotations that are detailed below.


Human    92 YCGAVLVHPQWLLTAAHC----RKKVFRVRLGHYSLSPVYESGQQMFQGVKSI-PHPGYSHPGHS 151
            :||..|:..:.:||||||    :..|...|||........:........||.. .||.:|:|...
  Fly   102 FCGGTLISDRHVLTAAHCHYSPQGSVNIARLGDLEFDTNNDDADPEDFDVKDFTAHPEFSYPAIY 166

Human   152 NDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTK-SPQVHFPKV--LQCLNISVLS 213
            ||:.:::|:|.:.......|..:.......||..:..|||..: .|:....|:  ::..|...  
  Fly   167 NDISVVRLSRPVTFNDYKHPACLPFDDGRLGTSFIAIGWGQLEIVPRTENKKLQKVKLYNYGT-- 229

Human   214 QKRC------EDAYPRQID-DTMFCAGDKAGRDSCQGDSGGPVV-------CNGSLQGLVSWGDY 264
              ||      .|..|...: .|..|.|....:|:|.|||||||:       |...:.|:.|.| .
  Fly   230 --RCRITADRNDELPEGYNATTQLCIGSNEHKDTCNGDSGGPVLIYHMDYPCMYHVMGITSIG-V 291

Human   265 PCARPNRPGVYTNLCKFTKWIQETIQAN 292
            .|..|:.|.:||.:..:..||::.:..|
  Fly   292 ACDTPDLPAMYTRVHFYLDWIKQQLAKN 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KLK5NP_036559.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 37..68
Tryp_SPc 66..285 CDD:214473 57/214 (27%)
CG11842NP_651662.1 Tryp_SPc 73..315 CDD:238113 59/217 (27%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.