Protein Alignment KLK5 and CG10232

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_651175.4
• Gene: CG10232 / 42800
• FlyBaseID: FBgn0039108
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 316
• Identity: 83/316 - (26%)
• Similarity: 133/316 - (42%)
• Gaps: 65/316 - (20%)

Human    13 CALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHT 77
            ||:.|..:.....|.     :.|..|.|.:|:...|            .....|:..|:....:.
  Fly   220 CAIDTRRIDSDKRHY-----ICCPEPGNVLPTSCGQ------------APPLYRMAYGTAARPNE 267

Human    78 QPWQAALLLRPNQL-----YCGAVLVHPQWLLTAAHCRKK---------VFRVRLGHYSL----- 123
            .||.|.|:....:|     .|...|::.:::||||||..|         :.|||||.:.:
  Fly   268 YPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTDLVLRRVRLGEHDITTNPD 332

Human   124 --------SPVYESGQQMFQGVKSIPHPGYSHPGH-SNDLMLIKLNRRIRPTKDVRPINV-SSHC 178
                    :|..|.|.:.|.     .|..|.:... .:|:.|::|...:|.|.::.||.| ....
  Fly   333 CDFTGNCAAPFVEIGIEYFN-----VHEQYFNTSRFESDIALVRLQTPVRYTHEILPICVPKDPI 392

Human   179 PSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQK-RCEDAYPRQIDDTMFCAGDKAGRDSCQ 242
            |.......::|||.||:.:  :.:||  |:.:|...: .|:|......:::..||....|.|||:
  Fly   393 PLHNHPLQIAGWGYTKNRE--YSQVL--LHNTVYENRYYCQDKISFFRNESQICASGIRGEDSCE 453

Human   243 GDSGGPVV--CNGSLQ------GLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
            ||||||::  .|...|      |:||:|...|. ..:|||||....|..||:..::
  Fly   454 GDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCG-DRKPGVYTKTGAFFSWIKANLK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		5/30 (17%)
		Tryp_SPc	66..285	CDD:214473	72/256 (28%)
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	73/255 (29%)