Protein Alignment KLK5 and CG5246

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Alignment Length: 231
• Identity: 64/231 - (27%)
• Similarity: 114/231 - (49%)
• Gaps: 15/231 - (6%)

Human    65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRK---KVFRVRLGHYSLSPV 126
            :|:|.|.|......|:|.:::....:..||..::.|||:||||||.:   :..::..|  ::...
  Fly    40 TRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCMEWPIQYLKIVTG--TVDYT 102

Human   127 YESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSS--HCPSAGTKCLVSG 189
            ....:.:..|.|.  |..:..|.:.||:.||...:.|......:||.::|  ..|..|.|..::|
  Fly   103 RPGAEYLVDGSKI--HCSHDKPAYHNDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTG 165

Human   190 WGTTKSPQVHFPKVLQCLNISVLSQKRCEDAY--PRQIDDTMFCAGDKAGRDSCQGDSGGPVV-C 251
            ||:||: ...:...||.::::.:....|:...  ...:.:...|...:.|..||.||||||:| .
  Fly   166 WGSTKT-WGRYSTQLQKIDLNYIDHDNCQSRVRNANWLSEGHVCTFTQEGEGSCHGDSGGPLVDA 229

Human   252 NGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
            |.:|.|:|:||: .|| ...|.|:.::..:..||::
  Fly   230 NQTLVGVVNWGE-ACA-IGYPDVFGSVAYYHDWIEQ 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/2 (50%)
		Tryp_SPc	66..285	CDD:214473	62/226 (27%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	63/227 (28%)