Protein Alignment KLK5 and CG31266

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001138068.1
• Gene: CG31266 / 42071
• FlyBaseID: FBgn0051266
• Length: 282
• Species: Drosophila melanogaster
• Alignment Length: 312
• Identity: 76/312 - (24%)
• Similarity: 126/312 - (40%)
• Gaps: 70/312 - (22%)

Human     8 W-MWVLCALITALLLGVTEHV---------LANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDD 62
            | :.||..|....|.|.||.:         |||  :.....:..||.|
  Fly     5 WNLTVLLGLTLLALQGPTEAMRMRGEPLPGLAN--IERHRSTEAVPQG----------------- 50

Human    63 SSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLG---- 119
               |:|.|:.......||.|::....:...|||:::...|:||||.|    |.....|..|
  Fly    51 ---RVIGGTTAAEGNWPWIASIQNAYSYHLCGAIILDETWVLTAASCVAGLRPLNLLVVTGTVDW 112

Human   120 ------HYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIR---PTKDVRPINVS 175
                  :|::|.::             .|..:..|.:.||:.|::|:.:|.   .||::...::.
  Fly   113 WDLYAPYYTVSQIH-------------VHCNFDKPLYHNDIALLQLSSKIEFNDVTKNITLADID 164

Human   176 SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ--IDDTMFCAGDKAGR 238
            .  ...|.|...:|||::::... :.:.||..:.:.|....|.:....|  :|....|....||:
  Fly   165 E--LEEGDKLTFAGWGSSEAMGT-YGRYLQEASGTYLPVDACREKLQNQDDVDLGHVCVQMDAGQ 226

Human   239 DSCQGDSGGPVVCNGS-LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289
            .:|.||:|||::.... |.|:.:|| .||.| ..|.||.....:..||:.|:
  Fly   227 GACHGDTGGPLIDEQQRLVGIGNWG-VPCGR-GYPDVYARTAFYHDWIRTTM 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/30 (13%)
		Tryp_SPc	66..285	CDD:214473	59/238 (25%)
CG31266	NP_001138068.1	Tryp_SPc	52..275	CDD:238113	60/240 (25%)